Norchelerythrine from

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Tác giả: Byeol-Eun Jeon, Hyeon-Young Kim, Sang-Woo Kim, Tae-Jin Kim, Chan-Seong Kwon, Ji-Eun Lee, Sang Hun Lee, Youngseob Seo, Ho-Jin Shin

Ngôn ngữ: eng

Ký hiệu phân loại:

Thông tin xuất bản: Greece : International journal of oncology , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 463820

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Acute myeloid leukemia (AML) is the most prevalent form of leukemia in adults. The cornerstone of first‑line chemotherapy for AML has poor survival rates, underscoring the urgent need for development of novel therapeutic agents. Differentiation therapy targets the blockade of differentiation in myeloid progenitor cells. The present study screened 100 plant extracts native to South Korea to search for those with differentiation‑inducing activity in AML. Differentiation‑inducing activity was assessed by measuring CD11b expression using fluorescence activated cell sorting. Of these,

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