The development of wearable sensing platforms for continuous monitoring of sweat biomarkers has gained significant attention, particularly for lactate detection. This study presents the design and fabrication of a novel wearable lactate biosensor that integrates a flexible supercapacitor power supply with an advanced lactate sensing platform. The sensing platform features NiCo nanosheets electrodeposited onto nanocages of bimetallic CoFe Prussian Blue analogue (PBA), providing an optimal microenvironment for the immobilization of lactate oxidase (LOx) enzymes. The CoFe PBA nanocages act as efficient electrocatalysts for the reduction of hydrogen peroxide, enhancing the sensor's performance. The electrode exhibits a sensitivity of 262 μA mM