A negative feedback loop between small GTPase Rap1 and mammalian tumor suppressor homolog KrsB regulates cell-substrate adhesion in

• Tác giả: Megan E Arnold, Yulia Artemenko, Jane Borleis, Peter N Devreotes, Bianca N Fernandez, Tiffany Flores, Harper D McClave, Gengle Niu, Michael Paestella, Kelsey E Roberts
• Ngôn ngữ: eng
• Ký hiệu phân loại: 415.0182 Grammar of standard forms of languages Syntax of standard forms of languages
• Thông tin xuất bản: United States : Molecular biology of the cell , 2025
• Bộ sưu tập: NCBI
• ID: 464500

Tóm tắt

Cell adhesion to the substrate influences a variety of cell behaviors and its proper regulation is essential for migration, although details of the molecular pathways regulating cell adhesion during migration are lacking. Rap1 is a small GTPase that regulates adhesion in mammalian cells, as well as in