UNLABELLED: Heterosis, a key technology in modern commercial maize breeding, is limited by the narrow genetic base which hinders breeders from developing superior hybrid varieties. By integrating big data and functional genomics technologies, it becomes possible to create new super maize inbred lines that resemble hybrid varieties through the aggregation of multiple QTL parental advantage loci. In this study, we utilized a combination of resequencing and field selfing selection methods to develop three pyramiding QTL lines (PQLs) (PQL4, 6, and 7), each containing 15, 12, and 12 QTL loci respectively. Among the three PQLs, PQL6 (266.78 cm/119.39 cm) demonstrated hybrid-like performance comparable to the hybrid (276.96 cm/127.02 cm) ( SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s11032-025-01546-4.