Hemocompatible chitosan nanoparticle diallyl disulfide-modified polysulfone hollow fibre membrane with antithrombotic and antioxidant properties for haemodialysis applications.

• Tác giả: Siti Nur Afifi Ahmad, Pei Sean Goh, Ahmad Fauzi Ismail, Juhana Jaafar, Siti Hamimah Sheikh Abdul Kadir, Mohd Hafiz Dzarfan Othman, Yanuardi Raharjo, Djoko Santoso, Ira Sari Yudaniayanti, Muhamad Zulhilmi Zailani
• Ngôn ngữ: eng
• Ký hiệu phân loại: 005.3042 Programs
• Thông tin xuất bản: Netherlands : International journal of biological macromolecules , 2025
• Bộ sưu tập: NCBI
• ID: 468957

Tóm tắt

The study aims to enhance the biocompatibility of haemodialysis membranes to reduce mortality risks in end-stage renal disease (ESRD) patients by addressing oxidative stress and thrombus formation. A novel Chitosan Diallyl Disulfide Nanoparticle (CNP/DADS) complex was immobilised into PSF membranes at various concentrations. The most optimal membrane, with 0.3 wt% CNP, demonstrated the highest K