Genomic characteristics of ST6115 carbapenem-resistant

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Tác giả: Hong Du, Qizhao Gao, Feinan Qian, Xiaofang Xie, Yaxuan Zhai, Jie Zhu, Zhichen Zhu

Ngôn ngữ: eng

Ký hiệu phân loại:

Thông tin xuất bản: Switzerland : Frontiers in microbiology , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 469709

OBJECTIVES: The aim of this study is to characterize the genomic features of ST6115 carbapenem-resistant METHODS: The genome sequences of one ST6115 RESULTS: A comparable phylogenetic analysis revealed that ST6115 HD8428 and the majority of ST17 strains (9/12) were clustered on the same clade, which suggests a close relationship between two ST types. Additionally, HD8428 showed particularly close genetic similarity to HD11490, with a single-nucleotide polymorphism (SNP) difference of only 273. The analysis of the antibiotic resistance genes carried by the 13 strains revealed that all strains carry extended-spectrum β-lactamase (ESBL) genes. AST revealed that HD8428 exhibited resistance to a diverse range of antibiotics. The CONCLUSION: We report a clinical ST6115 strain HD8428 and identify the coexistence of
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