GPCRs in hypothalamic neurons and their roles in controlling food intake and metabolism.

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Tác giả: Ou Fu, Tian Qiu

Ngôn ngữ: eng

Ký hiệu phân loại:

Thông tin xuất bản: Switzerland : Frontiers in molecular neuroscience , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 469828

Thêm vào giỏ Liên kết toàn văn

G-protein coupled receptor (GPCR) subtypes within the hypothalamus play a pivotal role in maintaining body homeostasis, particularly in the regulation of food intake and energy metabolism. This review provides an overview of classical loss and gain-of-function studies on GPCRs related to feeding and metabolism, with a focus on emerging cell-type-specific investigations. These studies reveal that diverse GPCR-expressing neuronal populations are intricately linked to feeding and energy balance. We also discuss recent findings that highlight the interaction of distinct peptide-GPCR systems in modulating complex feeding behaviors.

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