WHAT IS ALREADY KNOWN ABOUT THIS TOPIC?: Scrub typhus is an acute infectious disease caused by WHAT IS ADDED BY THIS REPORT?: This study documents the first confirmed case of scrub typhus in Ningxia Hui Autonomous Region, China. The patient presented with characteristic clinical manifestations, including abnormal biochemical indicators and positive serum-specific IgM antibodies against scrub typhus. Epidemiological evidence suggests local acquisition of the disease. WHAT ARE THE IMPLICATIONS FOR PUBLIC HEALTH PRACTICE?: Enhanced surveillance and preventive measures for scrub typhus are essential in this region, particularly for individuals residing in or visiting areas where the disease may be endemic.