Effect of prostate volume on the predictive value of prostate-specific antigen density for prostate cancer.

• Tác giả: Rui Hu, Tengteng Jian, Zejun Liu, Ji Lu, Kai Yu, Ying Yu
• Ngôn ngữ: eng
• Thông tin xuất bản: China : Translational andrology and urology , 2025
• Bộ sưu tập: NCBI
• ID: 470913

Tóm tắt

 BACKGROUND: In clinical practice, we observed that some patients with larger prostate volume (PV) and prostate-specific antigen (PSA) values below 20 ng/mL still yielded negative biopsy results. We aim to establish a more precise volume range for guiding biopsies in patients with enlarged prostate glands. METHODS: We conducted a retrospective analysis of 424 cases involving patients who underwent prostate biopsy. The patients were categorized into three groups based on their body mass index: small (PV <
 45 cm RESULTS: In the multivariate logistic regression analysis, a statistically significant association was observed between prostate-specific antigen density (PSAD) ≥0.15 ng/mL/cm CONCLUSIONS: The likelihood of developing prostate cancer is higher in patients with small PVs (PV <
 45 cm