Sublobectomy versus lobectomy for peripheral small-sized pulmonary mucinous adenocarcinoma.

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Tác giả: Hiran C Fernando, Gening Jiang, Xiang Li, Zhaoxun Li, Xiao Song, Fujun Yang, Zhen Yang

Ngôn ngữ: eng

Ký hiệu phân loại: 599.6332 *Ungulates

Thông tin xuất bản: China : Journal of thoracic disease , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 471998

BACKGROUND: Pulmonary mucinous adenocarcinoma (PMA), a rare type of adenocarcinoma, remains controversial in terms of its associated prognosis. We conducted this study to compare the oncological outcomes of lobectomy and sublobectomy for peripheral small-sized PMA. METHODS: This retrospective observational study included all patients with peripheral small-sized (≤2 cm) clinical stage IA1-A2 PMA who underwent lobectomy or sublobectomy (with margin distances ≥2 cm or greater than tumor diameter) between January 2015 and December 2018. Recurrence-free survival (RFS) and overall survival (OS) were compared between the lobectomy and sublobectomy groups with Kaplan-Meier curves and log-rank tests. RESULTS: This study examined 279 patients, with 176 cases in the lobectomy group and 103 cases in the sublobectomy group. Recurrence occurred in 8 patients, and 6 patients died. Before and after propensity score matching (PSM), log-rank tests showed no statistical differences between the lobectomy and sublobectomy groups in terms of 5-year RFS (before PSM: 97.0% CONCLUSIONS: For peripheral small-sized PMA, sublobectomy yielded an RFS and OS comparable to those of lobectomy.
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