Perioperative utilization of angiotensin receptor-neprilysin inhibitor in patients with heart failure with reduced ejection fraction undergoing coronary artery bypass grafting-a narrative review.

• Tác giả: Sangram Keshari Behera, Ritwik Raj Bhuyan, Vijyant Devenraj, Manoj Durairaj, Atul Kumar Gupta, Mohd Azam Haseen, Sanjay Jain, Ambrish Khatod, Madhav Kumar, Sanjay Kumar, Tushar Kumar, Soumya Ranjan Mahapatra, Rajneesh Malhotra, Chandan Ray Mohapatra, Lingraj Nath, Amrutraj Nerlikar, Kaushal Pandey, Debasish Sahu, Neeraj Kumar Sharma, Arunkumar Ulaganathan, Abhay Singh Walia
• Ngôn ngữ: eng
• Ký hiệu phân loại: 297.1248 Sources of Islam
• Thông tin xuất bản: India : Indian journal of thoracic and cardiovascular surgery , 2025
• Bộ sưu tập: NCBI
• ID: 472686

Tóm tắt

 Heart failure with reduced ejection fraction (HFrEF) is frequently observed in patients undergoing coronary artery bypass grafting (CABG), and it significantly increases the risk of postoperative death while exerting a crucial influence on the recovery process following the surgical intervention. HFrEF is one of the prevalent risk factors for early readmission in patients who underwent CABG. Angiotensin receptor-neprilysin inhibitor (ARNI) has been recognized as a critical medical therapy in the management of HFrEF
  however, its efficacy and safety have yet to be corroborated in the context of CABG. Therefore, this opinion document developed by a group of cardiothoracic and vascular surgeons in India focuses on the utilization of ARNI for patients with HFrEF, including those undergoing or having undergone CABG. These opinions based on clinical experience include perioperative use of ARNI
  postoperative initiation of ARNI
  strategies for addressing challenges such as hyperkalemia, hypotension, and renal dysfunction
  and initiation of other foundational medical therapies in HFrEF management in the context of CABG.