Nghiên cứu thang điểm dự báo độ nặng ở bệnh nhân chấn thương sọ não=Research the scale for prediction severe in traumatic brain injury patients

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Tác giả: Bảo Hoàng Lê, Ngọc Bình Lê, Viết Hòa Lê, Dũng Ngô, Thị Mỹ Duyên Trần

Ngôn ngữ: vie

Ký hiệu phân loại:

Thông tin xuất bản: Y học cộng đồng, 2023

Mô tả vật lý: tr.143-150

Bộ sưu tập: Báo, Tạp chí

ID: 477570

Thêm vào giỏ

Nghiên cứu nhằm khảo sát nồng độ ADH huyết thanh và một số yếu tố nặng ở bệnh nhân chấn thương sọ não. Đồng thời đánh giá mối liên quan giữa sự biến đổi nồng độ ADH huyết thanh và một số yếu tố nặng từ đó xác định giá trị dự báo tiên lượng ở bệnh nhân chấn thương sọ não. Phương pháp nghiên cứu: Nghiên cứu mô tả cắt ngang, có theo dõi dọc và so sánh nhóm chứng. Trên 105 bệnh nhân trên 18 tuổi, nhập viện trong 72 giờ đầu sau chấn thương sọ não, được điều trị tại khoa Gây Mê Hồi sức Bệnh viện Trung Ương Huế và 116 người tham chiếu khỏe mạnh Kết quả: Nồng độ ADH khi nhập viện ở nhóm bệnh nhân chấn thương sọ não có các yếu tố tăng nặng như tổn thương não phối hợp là 59,80 ± 41,04 pg/ml, điểm Glasgow ≤8 là 50,58 ± 42,48 pg/ml, điểm Marshall ≥3 là 50,48 ± 40,43pg/ml, di lệch đường giữa >
5mm là 54,64± 43,78pg/ ml, có thở máy là 61,80 ± 40,67pg/ml tăng cao có ý nghĩa thống kê. Định lượng nồng độ ADH huyết thanh phối hợp với thang điểm Glasgow, điểm Marshall cùng với các xét nghiệm máu cơ bản có ý nghĩa về dự báo tử vong, diễn biến nặng và số ngày nằm điều trị hồi sức. Kết luận: Nghiên cứu đã cho thấy cái nhìn tổng quát về sự biến đổi, vai trò của ADH huyết thanh trong chấn thương sọ não.The study aimed to investigate serum ADH levels and some severe factors in patients with traumatic brain injury. At the same time, evaluate the relationship between changes in serum ADH levels and some severe factors, thereby determining the predictive value of prognosis in patients with traumatic brain injury . Subjects and methods: A descriptive cross-sectional study, with longitudinal follow-up and comparison of the control group. Over 105 patients, were hospitalized in the first 72 hours after traumatic brain injury, treated at the Anesthesiology Department of Hue Central Hospital, and 116 healthy reference people. Results: ADH concentration upon admission in the group of patients with traumatic brain injury with severe factors such as complex brain damage was 59.80 ± 41.04 pg/ml, Glasgow score ≤8 was 50.58 ± 42.48 pg/ml, Marshall score ≥3 is 50.48 ± 40.43pg/ml, midline shift >
5mm is 54.64± 43.78pg/ml, with mechanical ventilation is 61.80 ± 40.67pg/ml increased. Quantifying serum ADH levels combined with the Glasgow scale, Marshall score, and basic blood tests are meaningful in predicting death, severe progression, and number of days in resuscitation treatment. Conclusion: The study has shown an overview of the changes and role of serum ADH in traumatic brain injury.

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