Sự thay đổi một số chỉ số sinh lý - hóa sinh trước và sau chạy thận nhân tạo ở bệnh nhân bệnh thận mạn giai đoạn cuối lọc máu chu kỳ tại bệnh viện trường Đại học Y khoa Vinh=Changes in some physiological - biochemical indicators before and after hemodialysis in patients with end-stage renal disease at Vinh Medical University Hospital

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Tác giả: Thị Thùy Dương Trần

Ngôn ngữ: vie

Ký hiệu phân loại:

Thông tin xuất bản: Y học cộng đồng, 2023

Mô tả vật lý: tr.49-55

Bộ sưu tập: Metadata

ID: 477616

Thêm vào giỏ

Khảo sát sự thay đổi một số chỉ số sinh lý – hóa sinh trước - sau chạy thận nhân tạo và đánh giá hiệụ quả lọc máu thông qua chỉ số URR ở bệnh nhân bệnh thận mạn giai đoạn cuối tại Bệnh viện Trường Đại học Y khoa Vinh. Phương pháp nghiên cứu: Nghiên cứu mô tả cắt ngang được thực hiện tại Bệnh viện Trường Đại học Y khoa Vinh từ tháng 6/2023 đến tháng 11/2023 Kết quả nghiên cứu: Độ tuổi trung bình của nhóm nghiên cứu là 50,33 ±14,75
tỷ lệ nam/nữ chiếm 50,9%, nữ chiếm 49,1%
nguyên nhân gây bệnh nhiều nhất là do viêm cầu thận (41,8%). Các chỉ số sinh lý - hóa sinh trước và sau chạy thận thay đổi có ý nghĩa: huyết áp giảm sau chạy thận (từ 133,78 ± 7,77/72,05 ± 2,95 mmHg còn 131,56 ± 2,47/71,71 ± 2,885mmHg), Ure máu giảm từ 22,03 ± 5,9 xuống còn 6,40 ± 2,45 mmol/l (p<
0,05), Creatinin máu giảm từ 1002.07 ± 327,98 xuống còn 382,16 ± 179,90 umol/l (p<
0,05), natri máu giảm từ 143,56 ± 5,76 còn 140,2 ± 5,23 mmol/l, kali máu giảm từ 6,09 ± 0,75 còn 5,23 ± 1,16 mmol/l. Chỉ số URR trung bình là 68,55 ± 1,49. Trong đó có 67,3% ca lọc có chỉ số URR ≥65% sau 6 tháng, triệu chứng lâm sàng giảm đáng kể sau lọc máu, nhất là triệu chứng chán ăn mệt mỏi (giảm 58,3%), buồn nôn - nôn (giảm 50%). Kết luận: Phần lớn bệnh nhân bệnh thận mạn giai đoạn cuối đạt chỉ số URR sau lọc.To investigate the changes in some physiological - biochemical indicators before and after hemodialysis and evaluate the effectiveness of blood filtration through the URR index in patients with end-stage renal disease at Vinh University Medical University Hospital. Research methods: A cross-sectional descriptive study was conducted at Vinh University Medical University Hospital from June 2023 to November 2023. Research results: The average age of the study group was 50.33 ± 14.75
the male/female ratio was 50.9% and 49.1% respectively
the most common cause of the disease was glomerulonephritis (41.8%). The physiological - biochemical indicators before and after hemodialysis showed significant changes: blood pressure decreased after hemodialysis (from 133.78 ± 7.77/72.05 ± 2.95 mmHg to 131.56 ± 2.47/71.71 ± 2.885mmHg), blood urea decreased from 22.03 ± 5.9 to 6.40 ± 2.45 mmol/l (p<
0.05), blood creatinine decreased from 1002.07 ± 327.98 to 382.16 ± 179.90 umol/l (p<
0.05), blood sodium decreased from 143.56 ± 5.76 to 140.2 ± 5.23 mmol/l, blood potassium decreased from 6.09 ± 0.75 to 5.23 ± 1.16 mmol/l. The average URR index was 68.55 ± 1.49. Among them, 67.3% of the cases had a URR index ≥65% after 6 months, with significant reduction in clinical symptoms after blood filtration, especially loss of appetite and fatigue (reduced by 58.3%), nausea - vomiting (reduced by 50%). Conclusion: Most end-stage renal disease patients achieved the URR index after filtration.

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