Khảo sát nồng độ canxi, phospho, PTH trên bệnh nhân suy thận mạn giai đoạn cuối đang lọc máu chu kỳ=Survey of calcium, phosphorus, and PTH levels in end-stage chronic kidney disease patients undergoing periodic hemodialysis

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Tác giả: Trần Kỳ Duyên Phan, Quốc Huy Trần

Ngôn ngữ: vie

Ký hiệu phân loại:

Thông tin xuất bản: Tạp chí Y học Việt Nam (Tổng hội Y học Việt Nam), 2024

Mô tả vật lý: tr.54-59

Bộ sưu tập: Metadata

ID: 477957

Thêm vào giỏ

Khảo sát nồng độ canxi, phospho, PTH trên bệnh nhân suy thận mạn giai đoạn cuối đang lọc máu chu kỳ, xác định tỉ lệ rối loạn khoáng xương và khảo sát mối liên quan giữa canxi, phospho, PTH với tuổi và thời gian điều trị lọc máu chu kỳ. Phương pháp nghiên cứu: Hồi cứu mô tả cắt ngang trên 133 bệnh nhân suy thận mạn giai đoạn cuối đang lọc máu chu kỳ đã thực hiện bộ xét nghiệm định kỳ tại bệnh viện Lê Văn Thịnh. Kết quả: Nồng độ canxi toàn phần hiệu chỉnh là 2,26 ± 0,28 mmol/L
phospho là 2,26 ± 0,28 mmol/L
trung vị nồng độ PTH là 280,30 pg/mL [159,20 - 506,30]. Tỉ lệ rối loạn khoáng xương có 78,2% canxi
95,5% phospho và 42,0% PTH. Có mối tương quan nghịch giữa tuổi với phospho và PTH, có mối tương quan thuận giữa thời gian lọc máu với canxi toàn phần hiệu chỉnh và PTH. Kết luận: Rối loạn khoáng xương là một rối loạn rất phổ biến trên bệnh nhân suy thận mạn giai đoạn cuối đang lọc máu chu kỳ.To investigate calcium, phosphorus, and parathyroid hormone (PTH) levels in end-stage chronic kidney disease (CKD) patients undergoing hemodialysis, determine the prevalence of mineral and bone disorders, and examine the correlation between calcium, phosphorus, PTH levels with age and duration of hemodialysis treatment. Methods: A retrospective cross-sectional study was conducted on 133 end-stage CKD patients undergoing regular hemodialysis, who had routine laboratory tests performed at Le Van Thinh Hospital. Results: The adjusted total calcium concentration was 2.26 ± 0.28 mmol/L, phosphorus was 2.26 ± 0.28 mmol/L, and the median PTH concentration was 280.30 pg/mL [159.20 - 506.30]. The prevalence of mineral and bone disorders was 78.2% for calcium, 95.5% for phosphorus, and 42.0% for PTH. There was an inverse correlation between age and phosphorus and PTH levels, and a positive correlation between duration of hemodialysis with adjusted total calcium and PTH levels. Conclusion: Mineral and bone disorders are highly prevalent in end-stage CKD patients undergoing regular hemodialysis.

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