Phân tích tình hình sử dụng kháng sinh colistin tại Bệnh viện Hữu Nghị Đa khoa Nghệ An năm 2023=Analysis of the situation of colistin antibiotic use at Nghe An Friendship General Hospital in 2023

0 Người đánh giá. Xếp hạng trung bình 0

Tác giả: Thị Soa Đặng, Thị Thu Hiền Hoàng, Thị Thúy Ngân Nguyễn, Thu Hằng Nguyễn, Thị Thủy Vũ

Ngôn ngữ: vie

Ký hiệu phân loại:

Thông tin xuất bản: Tạp chí Y học Việt Nam (Tổng hội Y học Việt Nam), 2024

Mô tả vật lý: tr.246-253

Bộ sưu tập: Metadata

ID: 478007

Thêm vào giỏ

Khảo sát và phân tích tính hợp lý trong việc sử dụng kháng sinh colistin tại Bệnh viện Hữu nghị Đa khoa Nghệ An năm 2023. Phương pháp: Nghiên cứu dựa trên 124 hồ sơ bệnh án của bệnh nhân nội trú có sử dụng colistin từ ngày 01/01/2023 đến 31/12/2023. Kết quả: Bệnh nhân điều trị tại Khoa Hồi sức Tích cực chiếm tỷ lệ sử dụng colistin cao nhất (22,6%). Loại nhiễm khuẩn phổ biến nhất là nhiễm khuẩn hô hấp kết hợp với nhiễm khuẩn huyết (21%), kế đến là nhiễm khuẩn hô hấp đơn thuần (16,1%). Tất cả bệnh nhân đều sử dụng colistin như liệu pháp thay thế, với phác đồ phối hợp colistin và meropenem chiếm 70,3%. Liều nạp được sử dụng trong 67,7% trường hợp, chủ yếu là 3.000.000 IU (46%). Liều duy trì thường là 2.000.000 IU x 2 lần/ngày (39,5%). 100% bệnh nhân dùng colistin qua đường tĩnh mạch, trong đó có 2 trường hợp kết hợp tiêm tĩnh mạch và khí dung. 94 bệnh nhân được điều trị theo vi khuẩn gây bệnh. Chỉ định và liều dùng colistin đều tuân theo hướng dẫn. Kết luận: Colistin chủ yếu được sử dụng như liệu pháp thay thế và phối hợp với các kháng sinh khác, thường được dùng liều nạp, và phù hợp với hướng dẫn điều trị theo vi khuẩn gây bệnh.To investigate and analyze the rationality of colistin antibiotic use at Nghe An General Friendship Hospital in 2023. Methodology: The study was based on 124 inpatient medical records involving the use of colistin from January 1, 2023, to December 31, 2023. Results: Patients in the Intensive Care Unit had the highest rate of colistin use (22.6%). The most common infections were respiratory infections combined with sepsis (21%), followed by isolated respiratory infections (16.1%). All patients received colistin as an alternative therapy, with the combination of colistin and meropenem accounting for 70.3%. A loading dose was used in 67.7% of cases, primarily at 3,000,000 IU (46%). The maintenance dose was typically 2,000,000 IU twice daily (39.5%). All patients were administered colistin intravenously, with two cases combining intravenous and aerosolized delivery. Ninety-four patients were treated based on the identified pathogen. Colistin prescriptions and dosing regimens adhered to the treatment guidelines. Conclusion: Colistin was predominantly used as an alternative therapy in combination with other antibiotics, commonly with a loading dose, and its use was aligned with pathogen-specific treatment guidelines.

1. Đọc trực tuyến

1. Đọc trực tuyến

Tạo bộ sưu tập với mã QR