Nghiên cứu sự đề kháng kháng sinh của các loại vi khuẩn gây bệnh thường gặp phân lập được từ mẫu bệnh phẩm mủ tại Bệnh viện trường Đại học Y-Dược Huế năm 2023=Study on antibiotic resistance of common pathogen bacteria isolated from pus specimens at Hue University Hospital in 2023

0 Người đánh giá. Xếp hạng trung bình 0

Tác giả: Thị Quỳnh Hạnh Nguyễn, Văn Bảo Thắng Phan, Đình Bình Trần

Ngôn ngữ: vie

Ký hiệu phân loại:

Thông tin xuất bản: Tạp chí Y học Việt Nam (Tổng hội Y học Việt Nam), 2024

Mô tả vật lý: tr.387-395

Bộ sưu tập: Metadata

ID: 478059

Thêm vào giỏ

Nghiên cứu sự đề kháng kháng sinh của các loại vi khuẩn gây bệnh thường gặp phân lập được từ bệnh phẩm mủ tại Bệnh viện Trường Đại học Y-Dược Huế năm 2023 nhằm đánh giá sự đề kháng kháng sinh của các vi khuẩn này. Đối tượng và phương pháp: Nghiên cứu mô tả cắt ngang trên 311 chủng vi khuẩn từ bệnh phẩm mủ có kết quả làm kháng sinh đồ tại bệnh viện Trường Đại học Y-Dược Huế năm 2023. Những bệnh nhân có kết quả nuôi cấy định danh vi khuẩn dương tính và có kết quả kháng sinh đồ lần đầu tại khoa Vi sinh, Bệnh viện Trường Đại học Y-Dược Huế trong 8 tháng từ tháng 01/5/2023 đến tháng 31/12/2023. Kết quả: 311 chủng vi khuẩn phân lập được ở bệnh phẩm mủ, gồm 31 loài vi khuẩn, trong đó 3 loài gây bệnh thường gặp nhất là S.aureus 36,3%, E.coli 15,8%, P.aeruginosa 14,5%. E.coli đề kháng với cefuroxime 100,0%, nhưng còn nh ạy cảm với một số loại kháng sinh như amikalin 100,0%, piperacillin+tazobactam chiếm 100,0%, tỷ lệ sinh ESBL 46,9%. đề kháng penicillin 95,4%, cefepime 77,5%, oxacillin 74,8%, erythromycin 72,6%, ngoài ra Staphylococcus aureus vẫn còn nhạy cảm với một số loại kháng sinh như linezolide 100,0%, chloramphenicol 98,7%, MRSA có tỷ lệ cao 75,2%. P.aeruginosa đề kháng với kháng sinh piperacillin+tazobactam 33,3%, nhạy cảm với kháng sinh ticarcillin+clavu 100,0%. Kết luận: Kết quả nghiên cứu định hướng cho chỉ định kháng sinh kinh nghiệm khi gặp phải các nhiễm trùng vết mổ, vết thương trên bệnh nhân ở bệnh viện Đại học Y-Dược Huế và có thể ở các bệnh viện khác.Research on antibiotic resistance of common pathogen bacteria isolated from pus samples at Hue University of Medicine and Pharmacy Hospital in 2023 to evaluate the antibiotic resistance of these bacteria. Subjects and methods: Cross-sectional descriptive study on 311 bacterial strains from pus specimens with antibiogram results at Hue University Hospital in 2023. Patients with definite culture results in positive bacteria list and first antibiogram results at the Department of Microbiology, Hue University Hospital for 8 months from May 1, 2023 to December 31, 2023. Results: 311 bacterial strains were isolated in pus specimens, including 31 bacterial species, of which the 3 most common pathogenic species are S.aureus 36.3%, E.coli 15.8%, P.aeruginosa 14.5%. E.coli is 100.0% resistant to cefuroxime, but is also sensitive to some antibiotics such as amikalin 100.0%, piperacillin+tazobactam accounts for 100.0%, ESBL production rate is 46.9%. resistant to penicillin 95.4%, cefepime 77.5%, oxacillin 74.8%, erythromycin 72.6%, in addition Staphylococcus aureus is still sensitive to some antibiotics such as linezolide 100.0%, chloramphenicol 98, 7%, MRSA has a high rate of 75.2%. P.aeruginosa was resistant to the antibiotic piperacillin+tazobactam 33.3%, sensitive to the antibiotic ticarcillin+clavu 100.0%. Conclusion: The research results guide the prescription of empirical antibiotics when encountering surgical and wound infections in patients at Hue University of Medicine and Pharmacy hospital and possibly in other hospitals.

1. Đọc trực tuyến

1. Đọc trực tuyến

Tạo bộ sưu tập với mã QR