Tăng nồng độ triglycerid huyết thanh ở quý III có liên quan với tăng huyết áp thai kỳ=Hypertriglyceridemia in third trimester associated with gestational hypertension

0 Người đánh giá. Xếp hạng trung bình 0

Tác giả: Việt Hà Nguyễn, Bá Nha Phạm, Mạnh Hùng Phạm

Ngôn ngữ: vie

Ký hiệu phân loại:

Thông tin xuất bản: Tạp chí Y học Việt Nam (Tổng hội Y học Việt Nam), 2024

Mô tả vật lý: tr.403-410

Bộ sưu tập: Metadata

ID: 478066

Thêm vào giỏ

During pregnancy, serum lipid levels, particularly triglycerides, increase and are associated with gestational hypertension. However, no studies have been conducted on this condition in Vietnam. Objective: To describe serum lipid levels in the third trimester of pregnancy and analyze the relationship between serum lipid levels and gestational hypertension. Methods: A descriptive study was conducted on 834 women in their third trimester who gave birth at Bach Mai Hospital from May 2023 to March 2024. Fasting serum levels of total cholesterol, LDL-cholesterol, HDL-cholesterol, and triglycerides were measured at 28-40 weeks of gestation. Odds ratios (OR) and 95% confidence intervals (CI) were calculated using a multivariate regression model. Results: The levels of total cholesterol, LDL-cholesterol, HDL-cholesterol, and triglycerides were 6.49±0.04, 3.37±0.34, 1.83±0.01, and 3.11±0.40 mmol/L, respectively. Elevated serum triglycerides were associated with gestational hypertension (OR 1.5, 95% CI 1.002 – 2.2, p=0.049) after adjusting for age, prepregnancy BMI, history of hypertension or preeclampsia in previous pregnancies, excessive gestational weight gain, primiparity, and gestational diabetes. Conclusion: In the third trimester, serum levels of total cholesterol, LDLcholesterol, HDL-cholesterol, and triglycerides were 6.49±0.04, 3.37±0.34, 1.83±0.01, and 3.11±0.40 mmol/L, respectively. Elevated triglyceride levels were associated with gestational hypertension in Vietnamese pregnant women.Khi có thai, nồng độ lipid huyết thanh tăng cao đặc biệt là triglycerid có liên quan đến tăng huyết áp thai kỳ. Tuy nhiên chưa có nghiên cứu về tình trạng này ở Việt Nam. Mục tiêu: Mô tả nồng độ một số thành phần lipid huyết thanh ở phụ nữ có thai 3 tháng cuối và phân tích mối liên quan giữa nồng độ lipid huyết thanh ở quý III thai kỳ và biến chứng tăng huyết áp thai kỳ. Phương pháp: nghiên cứu mô tả trên 834 phụ nữ có thai quý III sinh tại bệnh viện Bạch Mai từ tháng 5/2023 đến tháng 3/2024. Định lượng nồng độ cholesterol toàn phần, LDLcholesterol, HDL-cholesterol và triglycerid huyết thanh lúc đói ở tuổi thai 28-40 tuần. Tính tỷ số chênh và khoảng tin cậy 95% bằng mô hình hồi quy đa biến. Kết quả: Nồng độ cholesterol toàn phần, LDL-cholesterol, HDL-cholesterol, triglycerid huyết thanh lần lượt là 6,49±0,04
3,37±0,34
1,83±0,01 và 3,11±0,40 (mmol/L). Nồng độ triglycerid huyết thanh có liên quan với tăng huyết áp thai kỳ với OR 1,5 (khoảng tin cậy 95% 1,002 – 2,2, p=0,049) sau khi hiệu chỉnh theo tuổi, BMI trước mang thai, tiền sử tăng huyết áp hoặc tiền sản giật ở lần mang thai trước, tăng cân quá mức khi có thai, mang thai con so và đái tháo đường thai kỳ. Kết luận: Nồng độ cholesterol toàn phần, LDL-cholesterol, HDLcholesterol, triglycerid huyết thanh ở quý III thai kỳ lần lượt là 6,49±0,04
3,37±0,34
1,83±0,01 và 3,11±0,40 (mmol/L). Tăng nồng độ triglycerid huyết thanh có liên quan tới sự xuất hiện tăng huyết áp thai kỳ ở thai phụ Việt Nam.

1. Đọc trực tuyến

1. Đọc trực tuyến

Tạo bộ sưu tập với mã QR