Nhân một trường hợp chẩn đoán lơ xê mi cấp thể tiền tủy bào ở phụ nữ có thai tại Viện Huyết học - Truyền máu Trung ương=A case of diagnosis of acute promyelocytic leukemia in pregnancy at National Institute of Hematology and Blood Transfusion

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Tác giả: Quốc Khánh Bạch, Hà Thanh Nguyễn, Hồng Sơn Nguyễn, Quốc Nhật Nguyễn, Thu Chang Nguyễn

Ngôn ngữ: vie

Ký hiệu phân loại:

Thông tin xuất bản: Tạp chí Y học Việt Nam (Tổng hội Y học Việt Nam), 2024

Mô tả vật lý: tr.245-252

Bộ sưu tập: Báo, Tạp chí

ID: 478244

Thêm vào giỏ

Acute promyelocytic leukemia (APL) is a special subtype of acute myeloid leukemia. APL during pregnancy is a challenging situation, management of APL during pregnancy is an important issue for obstetricians, hematologists because it is often associated with coagulopathy, which can complicate seriously complicate the management of pregnancy, labor and delivery. Patients need to be closely monitored for clinical manifestations and tests to assess coagulation disorders. In addition, the management of APL in pregnancy currently remains quite complicated due to the potential teratogenic effects of ATRA and ATO chemotherapy. We report a case of diagnosis of APL during pregnancy, aiming to better understand the management of such complex cases.Lơ xê mi cấp thể tiền tủy bào là một phân nhóm đặc biệt của bệnh lơ xê mi cấp dòng tủy. APL khi mang thai là một tình huống đầy thách thức, quản lý APL khi mang thai là một vấn đề quan trọng đối với bác sĩ sản khoa, bác sĩ huyết học vì nó thường liên quan đến rối loạn đông máu, có thể làm phức tạp nghiêm trọng việc quản lý thai kỳ, chuyển dạ và sinh nở. Bệnh nhân cần được theo dõi chặt chẽ biểu hiện lâm sàng và xét nghiệm đánh giá tình trạng rối loạn đông máu. Ngoài ra, việc quản lý APL trong thai kỳ hiện nay vẫn còn khá phức tạp do tác dụng gây quái thai tiềm ẩn của hóa trị liệu ATRA và ATO. Chúng tôi báo cáo một trường hợp chẩn đoán APL trong khi mang thai, nhằm hiểu rõ hơn về cách xử trí những trường hợp phức tạp như vậy.

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