Tình trạng thiếu máu ở bệnh nhân ung thư đại trực tràng được chẩn đoán mới tại bệnh viện Đại học Y Hà Nội giai đoạn 2022-2023=Anaemia in newly diagnosed colorectal cancer patients at Hanoi Medical University hospital during 2022

Tình trạng thiếu máu ở bệnh nhân ung thư đại trực tràng được chẩn đoán mới tại bệnh viện Đại học Y Hà Nội giai đoạn 2022-2023=Anaemia in newly diagnosed colorectal cancer patients at Hanoi Medical University hospital during 2022 - 2023

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Tác giả: Thị Thanh Huyền Đỗ, Chí Thành Nguyễn, Kim Đồng Nguyễn, Quang Tùng Nguyễn, Thị Chúc Mai Nguyễn, Thị Thu Thuỳ Nguyễn, Văn Tuấn Phạm

Ngôn ngữ: vie

Ký hiệu phân loại:

Thông tin xuất bản: Tạp chí Y học Việt Nam (Tổng hội Y học Việt Nam), 2024

Mô tả vật lý: tr.435-443

Bộ sưu tập: Metadata

ID: 478301

Thêm vào giỏ

Determining the rate of anaemia, the severity of anaemia, the relationship between anaemia and tumour characteristics, and cancer markers CEA and CA19-9 in newly diagnosed colorectal cancer patients. Method: The crosssectional study was performed on 153 patients newly diagnosed with colorectal cancer at Hanoi Medical University Hospital. Results: 153 patients were diagnosed with colorectal cancer during the period 2022 to 2023 at Hanoi Medical University Hospital. The average age was 62.62±13,70 years old and 62.09% were male. Only 15.4% of patients were diagnosed at stage I, stage II and stage III were 44.44% and 43.79% respectively
T3 accounted for the highest per cent (56.21%) and T4 with 21.03%
the rate of distant metastasis to other organs is low (2.4%). The proportion of patients with anaemia at the time of diagnosis was 34%, mild anaemi accounted for the most at 61.12%, and moderate anaemia and severe anaemia were 35.40% and 3.48%, respectively. There are differences in TNM stage, N region lymph nodes, tumor size, CEA and CA19-9 test results, platelet count (PLT) between the anemic colorectal cancer group and the non-anaemic colorectal cancer group (p<
0.05 ). Conclusion: 34% of colorectal cancer patients at the time of diagnosis had anaemia, mainly mild anaemia (61%). Anaemia was correlated with TNM stage, regional lymph nodes, tumor size, CEA and CA19-9 results at diagnosis (p<
0.05).Xác định tỷ lệ thiếu máu, mức độ thiếu máu, mối liên quan giữa tình trạng thiếu máu với đặc điểm khối u, nồng độ CEA và CA19-9 ở bệnh nhân UTĐTT được chẩn đoán mới. Phương pháp: Nghiên cứu mô tả cắt ngang trên 153 bệnh nhân (BN) UTĐTT được chẩn đoán mới tại bệnh viện Đại học Y Hà Nội. Kết quả: Bệnh nhân UTĐTT có tuổi từ 62,62±13,70, nam chiếm chủ yếu 62,09%. Tỷ lệ phát hiện ở giai đoạn I thấp (15,4%), chủ yếu được phát hiện ở giai đoạn II (44,44%) và giai đoạn III (43,79%), khi khối u đã xâm lấn với T3 (56,21%) và T4 (21,03%)
tỷ lệ di căn xa ra các cơ quan khác thấp (2,40%). Tỷ lệ bệnh nhân thiếu máu tại thời điểm chẩn đoán là 33,99%, thiếu máu nhẹ chiếm nhiều nhất với 61,12%, thiếu máu vừa và thiếu máu nặng lần lượt là 35,40% và 3,48%. Có sự khác biệt về giai đoạn TNM, hạch vùng N, kích thước khối u, nồng độ CEA và CA19-9, số lượng tiểu cầu (PLT) giữa nhóm UTĐTT thiếu máu và UTĐTT không thiếu máu (p<
0,05). Kết luận: 33,99% bệnh nhân UTĐTT tại thời điểm được chẩn đoán có thiếu máu, chủ yếu là thiếu máu nhẹ (61,12%). Tình trạng thiếu máu có mối tương quan với giai đoạn TNM, hạch vùng, kích thước khối u, nồng độ CEA và CA19-9 tại thời điểm được chẩn đoán (p<
0,05).

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