Đặc điểm vi khuẩn gây nhiễm trùng huyết tại khoa Huyết học lâm sàng bệnh viện Trung ương Huế=Characteristics of bacteria causing sepsis in the Clinical Hematology department of Hue Central hospital

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Tác giả: Trần Hữu Hiếu Đặng, Bạch Thuỳ Trang Đoàn, Thất Minh Trí Tôn, Diên Hải Trương

Ngôn ngữ: vie

Ký hiệu phân loại:

Thông tin xuất bản: Tạp chí Y học Việt Nam (Tổng hội Y học Việt Nam), 2024

Mô tả vật lý:

Bộ sưu tập: Metadata

ID: 478309

Thêm vào giỏ

Nhiễm trùng huyết là một bệnh nặng, nguy cơ tử vong cao. Mục tiêu: Khảo sát tỷ lệ vi khuẩn gây nhiễm trùng huyết tại khoa Huyết học Lâm sàng, bệnh viện Trung ương Huế, khảo sát tình trạng đáp ứng với kháng sinh của một số vi khuẩn thường gặp. Phương pháp: mô tả cắt ngang, 45 bệnh nhân cấy máu (+) từ 4/2023- 4/2024, xử lý số liệu bằng phần mềm excel. Kết quả: 45 chủng vi khuẩn được nghiên cứu, tác nhân gây bệnh là: Klebsiella pneumoniae (28,9%), Escherichia coli (24,4%), Pseudomonas aeruginosa (17,8%)… Kháng sinh Aminoglycosid và Carbapenem còn nhạy cảm cao với Escherichia coli, Pseudomonas aeruginosa. Klebsiella pneumonia đề kháng với nhiều loại kháng sinh. Kết luận: Vi khuẩn Gr(-) gây bệnh nhiều nhất. Aminoglycosid và Carbapenem có hiệu quả với vi khuẩn Gr(-). Bệnh nhân bệnh máu có giảm bạch cầu hạt và giảm miễn dịch có nguy cơ nhiễm khuẩn huyết với nhiều loại vi khuẩn, kể cả những vi khuẩn hiếm gặp.Sepsis is a severe condition with a high risk of mortality. OBJECTIVE: To investigate the bacterial infection rates causing sepsis in the Clinical Hematology Department at Hue Central Hospital and examine the antibiotic response status of common bacteria. Methods: Crosssectional descriptive study, including 45 blood culture-positive patients from April 2023 to April 2024, with data analysis using Excel software. Results: 45 bacterial strains were studied, with the causative agents being: Klebsiella pneumoniae (28.9%), Escherichia coli (24.4%), Pseudomonas aeruginosa (17.8%), etc. Aminoglycosides and Carbapenems remained highly sensitive to Escherichia coli and Pseudomonas aeruginosa. Klebsiella pneumoniae showed resistance to multiple antibiotics. Conclusion: Gram-negative bacteria were the most common pathogens. Aminoglycosides and Carbapenems were effective against Gramnegative bacteria. Patients with blood disorders, granulocytopenia, and immunodeficiency were at risk of sepsis with various bacteria, including rare pathogens.

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