Nghiên cứu giá trị của chỉ số bạch cầu hạt chưa trưởng thành (IG) máu ngoại vi trong nhiễm khuẩn huyết=Study on the value of immature granulocyte index (IG) of peripheral blood in sepsis

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Tác giả: Thị Liên Phạm, Thị Hồng Hạnh Phùng

Ngôn ngữ: vie

Ký hiệu phân loại:

Thông tin xuất bản: Tạp chí Y học Việt Nam (Tổng hội Y học Việt Nam), 2024

Mô tả vật lý: tr.631-638

Bộ sưu tập: Metadata

ID: 478336

Thêm vào giỏ

Determine the predictive value of peripheral blood immature granulocyte index in patients with sepsis. Find out the relationship between immature granulocyte index and some characteristics in patients with sepsis. Methods: A cross-sectional descriptive study Results: The study was carried out on 240 healthy people, 65 infected patients and 300 sepsis patients treated at Thanh Nhan hospital. The value range of the IG index in normal people is: IG# = 0.0158 - 0.0194 G/L
IG% = 0.104 - 0.161%. The median of the IG number of the sepsis group is 0.11 G/L, the median of the IG ratio of the sepsis group is 0.9%. Compared to the infected group: The cut off point of the IG count is 0.085 G/L, which has a suggestive value for the diagnosis of sepsis with a fairly high specificity of 74%, sensitivity of 59% and area under the curve of 0.694. The cut off point of the IG ratio is 0.75%, which has a suggestive value for the diagnosis of sepsis with a fairly high specificity of 80%, sensitivity of 57% and area under the curve of 0.712. The number of IG and IG percentage has a moderate positive correlation with the number of white blood cells, a very weak positive correlation with PCT and SOFA. Conclusion: Immature granulocytes have value in suggesting the diagnosis of sepsis.Xác định giá trị dự đoán của chỉ số bạch cầu hạt chưa trưởng thành máu ngoại vi ở bệnh nhân nhiễm khuẩn huyết. Tìm hiểu mối liên quan chỉ số bạch cầu hạt chưa trưởng thành với một số đặc điểm ở bệnh nhân nhiễm khuẩn huyết. Phương pháp nghiên cứu: Nghiên cứu mô tả cắt ngang có nhóm chứng. Kết quả: Nghiên cứu được thực hiện trên 240 người khỏe mạnh, 65 bệnh nhân nhiễm trùng và 300 bệnh nhân nhiễm khuẩn huyết được điều trị tại bệnh viện Thanh Nhàn. Ghi nhận khoảng giá trị của chỉ số IG ở người bình thường là: IG# = 0,0158 - 0,0194 G/L
IG% = 0,104 - 0,161%. So với nhóm nhiễm trùng: Điểm cắt của số lượng IG là 0,085 G/L có giá trị gợi ý chẩn đoán nhiễm khuẩn huyết với độ đặc hiệu khá cao 74%, độ nhạy là 59% và diện tích dưới đường cong là 0,694. Điểm cắt của tỷ lệ IG là 0,75% có giá trị gợi ý chẩn đoán nhiễm khuẩn huyết với độ đặc hiệu khá cao 80%, độ nhạy là 57% và diện tích dưới đường cong là 0,712. Số lượng IG và phần trăm IG có mối tương quan thuận vừa với số lượng bạch cầu, tương quan thuận rất yếu với PCT và SOFA. Kết luận: Bạch cầu hạt chưa trưởng thành có giá trị gợi ý chẩn đoán nhiễm khuẩn huyết.

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