Đặc điểm một số chỉ số xét nghiệm đông cầm máu trên bệnh nhân chấn thương sọ não tại bệnh viện Hữu nghị Việt Đức=Characteristics of some hemostasis test indices in traumatic brain injury patients at Viet Duc University hospital

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Tác giả: An Sơn Đoàn, Thu Hạnh Nguyễn, Văn Chỉnh Nguyễn, Thị Hằng Trần, Thị Kiều My Trần, Thị Thanh Huyền Trần, Thị Thu Hiền Trịnh

Ngôn ngữ: vie

Ký hiệu phân loại:

Thông tin xuất bản: Tạp chí Y học Việt Nam (Tổng hội Y học Việt Nam), 2024

Mô tả vật lý: tr.730-736

Bộ sưu tập: Metadata

ID: 478356

Thêm vào giỏ

Chấn thương sọ não (CTSN) là bệnh lý ngoại khoa với tỷ lệ tử vong cao và để lại di chứng nặng nề, rối loạn đông máu (RLĐM) càng làm nghiêm trọng tình trạng của người bệnh. Mục tiêu: Mô tả đặc điểm một số chỉ số xét nghiệm đông cầm máu trên bệnh nhân CTSN tại bệnh viện Hữu nghị Việt Đức. Đối tượng và phương pháp nghiên cứu: mô tả cắt ngang, tiến cứu trên 297 bệnh nhân CTSN. Kết quả: Tỷ lệ RLĐM là 18,2%, chủ yếu giảm fibrinogen và tiểu cầu. Tỷ lệ tử vong ở nhóm có RLĐM (16,7%) cao hơn so với nhóm không có RLĐM (0,8%). Mức độ CTSN càng nặng thì tỷ lệ giảm fibrinogen càng cao. Tỷ lệ giảm fibrinogen ở nhóm có phẫu thuật (14,0%) cao hơn nhóm không phẫu thuật (3,4%). Kết luận: Tỷ lệ RLĐM chung ở bệnh nhân CTSN là 18,2%. RLĐM chủ yếu là giảm fibrinogen và giảm tiểu cầu mức độ nhẹ. Tỷ lệ RLĐM cao ở bệnh nhân CTSN có liên quan đến mức độ chấn thương, tình trạng phẫu thuật.Traumatic brain injury (TBI) is a surgical condition with a high mortality rate and severe sequelae. Coagulation disorders further exacerbate the patient’s condition. Objectives: To describe the characteristics of some hemostasis test indices in TBI patients at Viet Duc University Hospital. Subjects and Methods: A cross-sectional, prospective study was conducted on 297 TBI patients. Results: The rate of coagulation disorders was 18.2%, mainly due to decreased fibrinogen and platelets. The mortality rate in the group with coagulation disorders (16.7%) was higher than in the group without coagulation disorders (0.8%). The more severe the TBI, the higher the rate of decreased fibrinogen. The rate of decreased fibrinogen in the surgical group (14.0%) was higher than in the non-surgical group (3.4%). Conclusion: The overall rate of coagulation disorders in TBI patients was 18.2%. Coagulation disorders were mainly mild decreases in fibrinogen and platelets. The high rate of coagulation disorders in TBI patients was related to the severity of the injury, surgical status of TBI patients.

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