Bảo quản lạnh sâu mô van tim người để ghép tại Ngân hàng Mô, Bệnh viện Hữu nghị Việt Đức từ năm 2018 đến năm 2023=Preservation of human heart valves for replacementat the Tissue Bank, Viet Duc University Hospital from 2018 to 2023

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Tác giả: Đức Hùng Dương

Ngôn ngữ: vie

Ký hiệu phân loại:

Thông tin xuất bản: Khoa học và Công nghệ Việt Nam, 2024

Mô tả vật lý: tr.76-80

Bộ sưu tập: Metadata

ID: 478395

Thêm vào giỏ

The preservation of heart valve tissue with viable cells in tissue banks has ensured that surgeons always have a reserve of heart valves available, which can be actively and appropriately used according to the size and type needed for each patient requiring a replacement. This study was conducted to evaluate the collection, preparation, preservation, and transplant of heart valve homograft at the Tissue Bank, Viet Duc University Hospital, from October 2018 to October 2023. The results show that the Tissue Bank collected 78 heart valves from 39 donors. In which, the average age of donor patients was 36.2±17.3 (7-69)
men account for 76.9%. 100% of patients tested negative for HIV
97.4% were negative for HBV and HCV
9% of valves were removed due to morphology, hepatitis B infection, and hepatitis C infection. 100% of valves had negative microbiological results during tissue recovery, antibiotic soaking and postthawing. 51 homografts had been implanted into recipients with congenital or acquired heart valve conditions
the average age of transplant patients is 29.7±16.70 years (2-68)
the average storage time until transplantation is 9.4±10.2 months (6 days - 41.7 months)
36 patients have been alive/stable after transplantation, 3 patients have died.Việc bảo quản được mô van tim còn tế bào sống trong các ngân hàng mô đã giúp cho phẫu thuật viên luôn có nguồn van tim dự trữ, có thể sử dụng một cách chủ động và phù hợp với kích cỡ, chủng loại của từng bệnh nhân cần thay thế. Nghiên cứu này được thực hiện nhằm nhận xét tình hình thu nhận, xử lý, bảo quản và ghép mô van tim đồng loại tại Ngân hàng Mô, Bệnh viện Hữu nghị Việt Đức từ 10/2018 đến 10/2023. Kết quả cho thấy, Ngân hàng Mô đã thực hiện thu nhận 78 van tim từ 39 người hiến. Tuổi trung bình bệnh nhân hiến là 36,2±17,3 (7-69)
nam giới chiếm 76,9%. 100% người hiến có kết quả sàng lọc âm tính với HIV
97,4% âm tính với HBV và HCV
9% số van bị loại bỏ do các nguyên nhân: hình thái, nhiễm viêm gan B và viêm gan C. 100% số mẫu có kết quả vi sinh âm tính giai đoạn thu nhận mô, ngâm kháng sinh và trước khi ghép. Đã thực hiện ghép van tim bảo quản cho 51 bệnh nhân từ nhiều bệnh lý
tuổi của bệnh nhân ghép trung bình là 29,7±16,70 tuổi (2-68)
thời gian bảo quản đến khi ghép trung bình là 9,4±10,2 tháng (6 ngày đến 41,7 tháng)
36 bệnh nhân sống/ổn định sau ghép, 3 bệnh nhân đã tử vong.

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