Tình hình nhiễm khuẩn các sản phẩm mô ghép đồng loài tại Ngân hàng Mô, Bệnh viện Hữu nghị Việt Đức=Situation contamination of tissue allograft products at the Tissue Bank, Viet Duc University Hospital

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Tác giả: Đức Hùng Dương

Ngôn ngữ: vie

Ký hiệu phân loại:

Thông tin xuất bản: Khoa học và Công nghệ Việt Nam, 2024

Mô tả vật lý: tr.65-70

Bộ sưu tập: Metadata

ID: 478411

Thêm vào giỏ

The current status of tissue allograft infection, rate and common microorganisms in tissue banks are missing data in the current medical literature in Vietnam. Objective: Describe the infection situation and characteristics of microorganisms on allografts. Subjects and methods: Descriptive, retrospective study on 774 samples from 155 allograft batches preserved at the Tissue Bank of Viet Duc University Hospital. Results: The overall infection rate for tissue allograft was 12/155 (7.74%) before decontamination, 3/155 (1.94%) after decontamination. The rate of positive bacterial cultures for each type of tissue was 3/3 (100%) for tracheal, 6/36 (16.7%) for tendons, and 3/63 (4.76%) for blood vessels. In the post-decontamination phase, the infection rates for tracheal and blood vessels were 2/3 (66.67%) and 1/63 (1.59%), respectively. The isolated bacteria were mainly aerobic bacteria, mostly Staphylococcus. Multi-resistant bacteria strains with high pathogenicity appeared: Klebsiella pneumoniae, Pseudomonas aeruginosa, Staphylococcus aureus - MRSA (+).Thực trạng nhiễm khuẩn mô ghép, tỷ lệ và loại vi sinh vật phổ biến trong các ngân hàng mô là những dữ liệu còn thiếu trong y văn hiện nay tại Việt Nam. Mục tiêu của nghiên cứu này: Mô tả tình hình nhiễm khuẩn và đặc điểm vi khuẩn phân lập được trên mô ghép đồng loài. Đối tượng và phương pháp nghiên cứu: Nghiên cứu mô tả, hồi cứu trên 774 mẫu từ 155 lô mô ghép đồng loài được bảo quản tại Ngân hàng Mô, Bệnh viện Hữu nghị Việt Đức. Kết quả: Tỷ lệ nhiễm khuẩn chung đối với mô ghép là 12/155 (7,74%) trước khử nhiễm, 3/155 (1,94%) sau khử nhiễm. Tỷ lệ cấy khuẩn dương tính với từng loại mô khí quản 3/3 (100%) và gân 6/36 (16,7%), mạch máu 3/63 (4,76%). Giai đoạn sau khử nhiễm, mô khí quản và mạch máu có tỷ lệ nhiễm lần lượt là 2/3 (66,67%) và 1/63 (1,59%). Vi khuẩn phân lập được chủ yếu là vi khuẩn ái khí, nhiều nhất là Staphylococcus. Xuất hiện các chủng vi khuẩn đa kháng, khả năng gây bệnh và độc lực cao như: Klebsiella pneumoniae, Pseudomonas aeruginosa, Staphylococcus aureus - MRSA (+).

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