Nghiên cứu tác dụng điều trị của thuốc chẹn beta giao cảm propranolol ở bệnh nhân trướng tĩnh mạch thực quản do xơ gan

 0 Người đánh giá. Xếp hạng trung bình 0

Tác giả: Như Thế Phạm, Viết Dũng Trần

Ngôn ngữ: vie

Ký hiệu phân loại: 610 Medicine and health

Thông tin xuất bản: Y học việt nam, 2011

Mô tả vật lý: 61-68

Bộ sưu tập: Metadata

ID: 480756

Research objectives: To assess the treatment effects of Propranolol in esophageal varices due to cirrhosis. Subjects: 34 patients were diagnosed with esophageal varices due to cirrhosis in Digestive Internal Department of Hue Central hospital from October, 2006 to May, 2007. Methods: The patients were recorded the parameters of vessels, blood pressure, bleeding, arterial vein diameter by ultrasound and were assessed the levels of esophageal varices by endoscopy. Then they were treated with Propranolol to reduce heart rate 25 percents and blood pressure 20 mmHg compared to before treatment. They were used Propranolol during a month, then were tested all the parameters of bleeding, portal vein diameter and the levels of esophageal varices to assess the effects of treatment. Results: Propranolol helps to reduce portal vein diameter by ultrasound: portal vein diameter before the average treatment is 15.74 + or - 2.19 mm, after the average treatment is 13.26 + or - 2.19mm, the change was statistically significant, with p 0.05. Propranolol helps to reduce the size of esophageal varices by endoscopy: 7 patients (20.6 percent) reduced the level of esophageal varices, 26 patients (76.5 percent) kept the level of esophageal varices. Propranolol also helps to reduce the risk of bleeding due to rupture of esophageal varices: there were 9 patients (26.5 percent) bleeding before treatment, but after treatment, only 4 patients (11.8 percent) bleeding, the differences were statistically significant, with p 0.05. Response rate with Propranolol was 82.3 percent, in particular, good response rate was 20.6 percent, moderate response rate was 61.8 percent. No response rate was only 17.7 percent. Condusions: Through the effect to reduce the portal vein pressure, Propranolol reduces the portal vein diameter by ultrasound, the size of esophageal varices by endoscopy, and reduce the risk of bleeding due to rupture of esophageal varices.
Tạo bộ sưu tập với mã QR

THƯ VIỆN - TRƯỜNG ĐẠI HỌC CÔNG NGHỆ TP.HCM

ĐT: (028) 71010608 | Email: tt.thuvien@hutech.edu.vn

Copyright @2024 THƯ VIỆN HUTECH