Background: Colonoscopy is a flexible method of exploration is very valuable function to confirm the diagnosis of colorectal disease. Objective: Some remarks colorectal disease colorectal endoscopic hose on 4500 case in gastrointestinal endoscopy rooms at Viet-Tiep Hai Phong hospital. Methods: descriptive cross-sectional. Results: Study 4500 cases of colorectal endoscopy, the authors found: the age group most having 40 to 69 accounted for 71.26 percent. Ratio male/female is 1.13. Patients with colorectal polyps, the highest proportion (15:48 percent). Primary polyps in the rectum and sigmoid colon (85.21 percent). Rectal inflammation (48.43 percent), colitis sigma (46.50 percent). Sigma ulcerative colitis (33.01 percent), rectal ulcer (30.09 percent). Rectum tumor (41.48 percent), sigmoid colon tumor (36.17 percent), colon tumor occupied the lowest level (2.83 percent). Conclusions: Nearly half the cases laparoscopic colorectal lesions. The rate of inflammatory disease and colorectal polyp account for most and mainly in the rectum and sigmoid colon.