HÀM LƯỢNG POLYPHENOL TỔNG, HOẠT TÍNH KHÁNG OXI HÓA, KHÁNG KHUẨN VÀ KHÁNG NẤM CỦA CAO CHIẾT LÁ ỔI SẺ (Psidium guajava L.)

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Tác giả: Thị Tuyết Nhung Đỗ, Thị Kiều Tiên Đoàn, Thị Thảo Lê, Cường Quốc Nguyễn, Thị Như Ý Nguyễn, Quang Đệ Trần

Ngôn ngữ: vie

Ký hiệu phân loại:

Thông tin xuất bản: Tạp chí Khoa học và Công nghệ Cần Thơ, 2024

Mô tả vật lý: tr.30

Bộ sưu tập: Metadata

ID: 481119

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Guava leaves, a common source of raw material in the Mekong Delta, possess various biological activities such as antioxidant, antibacterial, anti-inflammatory, antidiabetic, and anti-diarrheal properties. However, this rich and naturally regenerative medicinal source has not been efficiently and properly exploited. This study investigated the total polyphenol content, antioxidant, antibacterial, and antifungal activities of methanol extract of guava leaves by maceration method. Antioxidant activity was performed by DPPH and ABTS methods, while antibacterial and antifungal activities were tested by the dilution method for concentration. The results showed that guava leaf extract had the strongest antioxidant activity on the DPPH method (EC50=19.36µg/mL) and the most effective inhibition against Gram-positive bacterium Staphylococcus aureus (IC50=64.00±4.57µg/mL). These findings open up avenues for the development of natural biologically active products from guava leaves.Lá ổi, một nguồn nguyên liệu phổ biến ở Đồng bằng sông Cửu Long, sở hữu nhiều hoạt tính sinh học như kháng oxi hóa, kháng khuẩn, kháng viêm, kháng đái tháo đường, điều trị tiêu chảy,... Tuy nhiên, nguồn dược liệu phong phú và tái sinh tự nhiên này chưa được khai thác hiệu quả và đúng mức. Nghiên cứu này khảo sát hàm lượng polyphenol tổng, hoạt tính kháng oxi hoá, kháng khuẩn và kháng nấm của cao chiết methanol lá ổi sẻ theo phương pháp ngâm dầm. Hoạt tính kháng oxi hoá được thực hiện trên hai phương pháp DPPH và ABTS, hoạt tính kháng khuẩn và kháng nấm được thực hiện theo phương pháp pha loãng nồng độ. Kết quả cho thấy cao lá ổi cho hoạt tính kháng oxi hoá mạnh nhất trên phương pháp DPPH (EC50=19,36µg/mL) và ức chế tốt nhất vi khuẩn Gram (+) Staphylococcus aureus (IC50=64,00±4,57µg/mL). Kết quả khảo sát mở ra hướng phát triển các sản phẩm hoạt tính sinh học thiên nhiên từ lá ổi.

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