Study 150 patients diagnosed with simple goiter and underwent thyroid surgery for simple goiter disease at The Oncology Hospital of Can Tho City from 05/2010 to 11/2010. The median age of patients was 45,3 + or - 13,6 (range 18-78) years. Ratio male/female 1/8. Goiter of grade III or higher accounted for 79.33 percent. The concentration of FT3, FT4, TSH serum levels in normal limits. Simple goiter was 83.34 percent on ultrasound . FNA cytology before surgery was 82 percent for simple goiter. Near-total thyroidectomy for 48 percent, total thyroidectomy for 22 percent, lobectomy for 30 percent. The average surgical time 88.75 + or - 15.39 minutes. The weight of thyroid were cut on average 44.71 + or - 21.44 grams. Hospital stays on average 5.13 + or - 3.54 days. Results as soon as possible to discharge 94 percent on good, 4 percent on average. Re-examination after 3 months of surgery was 98.15 percent on good, 1.15 percent on average.