Đặc điểm suy giảm trí nhớ và một số yếu tố liên quan ở bệnh nhân động kinh cơn lớn theo dõi điều trị tại Bệnh viện Tâm thần Hải Phòng=Characteristics of memory impairment and related factors in patients with grand mal epilepsy following treatment at Hai Phong Psychiatric Hospital

0 Người đánh giá. Xếp hạng trung bình 0

Tác giả: Đức Thắng Đàm, Thị Ngân Vũ

Ngôn ngữ: vie

Ký hiệu phân loại:

Thông tin xuất bản: Tạp chí Khoa học Sức khỏe, 2024

Mô tả vật lý: tr.76

Bộ sưu tập: Metadata

ID: 482393

Thêm vào giỏ

ABSTRACT: Describe the clinical characteristics of memory impairment in patients with grand mal epilepsy following treatment at Hai Phong Psychiatric Hospital and analyze some factors related to memory impairment in the above patient group. Research subjects: 151 patients diagnosed with grand mal epilepsy (G40.6) from 20 to 64 years old, under the community mental health care program managed by Hai Phong Psychiatric Hospital, monitored and treated at medical stations, in the period from September 2022 to September 2023. Results: The average MQ score of the entire research group was 89,24±12,13 points, of which 62/151 patients had MQ scores below average (less than 90 points), corresponding to the rate of patients with memory impairment of 41.05%, the most common symptoms is immediate memory impairment, followed by short-term memory impairment, and long-term memory impairment. Patients with an age of onset under 20 years old have a 3.24 times higher risk of memory impairment than patients with an age of onset ≥ 20 years old (p=0.0005). Patients with epilepsy for ≥ 20 years have a 2.8 times higher risk of memory impairment than those with epilepsy for <
20 years (p = 0.0006). The higher frequency of seizures, the higher risk of memory impairment (p <
0.001). Patients using Phenobarbital had a 2.96 times higher risk of memory impairment than patients not using Phenobarbital (p = 0.002).Mục tiêu nghiên cứu: Mô tả đặc điểm lâm sàng suy giảm trí nhớ ở bệnh nhân động kinh cơn lớn theo dõi điều trị tại Bệnh viện Tâm thần Hải Phòng và phân tích một số yếu tố liên quan đến suy giảm trí nhớ ở nhóm bệnh nhân trên. Đối tượng nghiên cứu: 151 bệnh nhân được chẩn đoán động kinh cơn lớn (G40.6) từ 20 đến 64 tuổi, thuộc chương trình chăm sóc sức khoẻ tâm thần cộng đồng do Bệnh viện Tâm thần Hải Phòng quản lý, theo dõi và điều trị tại các trạm Y tế từ tháng 09/2022 đến tháng 09/2023. Phương pháp nghiên cứu: Nghiên cứu mô tả, cắt ngang. Kết quả: Điểm trung bình MQ của cả nhóm nghiên cứu là 89,24±12,13 điểm, có 62/151 bệnh nhân có điểm MQ dưới trung bình (<
90 điểm), tương ứng với tỉ lệ bệnh nhân suy giảm trí nhớ là 41,05%, hay gặp nhất là suy giảm trí nhớ tức thì, sau đó là suy giảm trí nhớ ngắn hạn, và suy giảm trí nhớ dài hạn. Bệnh nhân khởi phát bệnh khi dưới 20 tuổi có nguy cơ suy giảm trí nhớ cao gấp 3,24 lần so với bệnh nhân có tuổi khởi phát ≥ 20 tuổi (p=0,0005). Bệnh nhân bị bệnh ≥ 20 năm nguy cơ suy giảm trí nhớ gấp 2,8 lần so với người bị bệnh <
20 năm (p = 0,0006). Bệnh nhân có tần suất cơn càng dày thì nguy cơ suy giảm trí nhớ càng cao (p <
0,001). Bệnh nhân dùng Phenobarbital nguy cơ suy giảm trí nhớ gấp 2,96 lần so với không sử dụng Phenobarbital (p = 0,002).

1. Đọc trực tuyến

1. Đọc trực tuyến

Tạo bộ sưu tập với mã QR