Objectives: to investigate the effects of transplantation of human umbilical cord epithelial stem cells on the healing of experimentally induced burn wounds in rabbits. Subjects and methods: 30 healthy rabbits were given full-thickness thermal bums, each rabbit had two bum wounds areas on back. They was divided to 3 group. Each of them are 10 rabbits with 20 bum wounds. Firt goup were covered by umbilical cord epithelial stem cells membrane. Second were covered by Silvirin. Third group were covered by transwell membrane after necrosis tissue earty-exdsion on 3th day of bum. The group 2nd and 3th was used as controls. Results: the epithelization rate of firt group and 2nd, 3th at 14 day period after the transplantation had a statistical difference. The complete healing rate of bum wounds in firt group was higher than that in 2nd, 3th group (60 vs 50 percent, 45 percent), at period of 17-24 days after indudng bum injuries. Conclusions: human umbilical cord epithelial stem cells enhanced bum wound healing faster than the controls.