Artificial Intelligence is undergoing a superior development phase and can potentially create significant changes in people’s daily lives. In teaching, AI is introducing new teaching and learning methods, which have been tested in many countries with varying degrees of development and success. This article aims to analyze the opportunities, challenges, and future impacts of AI in combination with active teaching methods at universities. The article evaluates the changes that AI brings to teaching and the difficulties when applying AI to university teaching. It also proposes some key solutions to address these issues. AI is opening new opportunities in teaching, from personalizing the learning process to providing access to the knowledge and skills necessary for the 21st century. However, applying active teaching methods combined with AI in university teaching also faces challenges, from ensuring teaching quality to ensuring that AI does not create discrimination. This article proposes some solutions to address these issues, from training teachers about AI to developing policies to ensure that AI is used fairly and transparently.