Introduction: The application of Transcranial Doppler Sonography - TDS to survey cerebral blood vessels is one of the common methods today. Objective: To identify the relation between the changes in hemokinesis of primary cerebral vessels and some risk factors to high blood pressure. Samples: 112 hypertention patients who were being treated at Cardiology Division, Internal Medicine Department between June 2008 and June 2009 and 49 ordinary people. Research methods: descriptive and prospective study. Results: Velocity among patients with diabetes and Lipid RL varied much more than that amongst smokers, in which the velocity reduced at 24 percent, the maximum velocity decreased 21 percent, the pulse increased 13 percent, anti-pulse index increased 9 percent. Diabetes and lipid disorder are risky factors to disordered hemokinesis of primary cerebral vessels: average velocity (OR equal to: 8,6-13,9
7,4-12,4 (p0,05)), pulse (OR equal to: 9,8-15,5
11,7-21,5 (p0,05)), (OR equal to: 6,3-10,4
6,6-11,3 (p0,05))
maximum velocity (OR equal to: 2,5-3,9
1,5-3,5 (p0,05))
Smoking does not affect the maximum velocity (p0,05), but makes average velocity, pulse and anti-pulse index changed with OR at: 2,6-4,9 (p0,05), 3,3-4,3 (p0,05), 2,8-3,6 (p0,05). Conclusion: There is a relation between the changes in hemokinesis indicators of cerebral vessels and risk factors to hypertension. (diabetes, blood lipid disorder).