The primary source of arsenic in soil is a combination of anthropogenic and natural weathering processes. The increased concentration of arsenic is a major issue due to its possible negative impacts on both ecosystems and human health. Considering these issues, this work conducts a rigorous and extensive investigation into the intricate dynamics of arsenic accumulation and contamination levels within soil matrices. The focus of this investigation is especially urgent, particularly in the context of the dioxin-contaminated environment. Specifically, the soil environment at Bien Hoa Airbase exhibits high levels of dioxin contamination.A look at the values of the contamination factor, which ranges from 2.8 to 17.3, suggests indicators of a non-natural origin for the arsenic found in the soils. In addition, the arsenic quantities measured vary significantly, ranging from 9.9 mg/kg to 66.2 mg/kg, and the high accumulation distributed almost the Northeast of the study site. This observed range exceeds the World Health Organization's (WHO) and Viet Nam's regulatory guidelines. The contamination level is much higher than the background arsenic concentration. These results emphasize how critical it is to address and lessen the effects of anthropogenic arsenic pollution on the ecosystem and public health.