Objective: identify effective intervention by community education to improve knowledge and practice in safe use of chemical pesticides. Method: designed intervention studies comparing before and after indicators of knowledge and practice in safe using chemical pesticides by the training intervention, communication, handouts
effective intervention. Data analysis by using EPIINFOR 6.0 software, calculate the variable rate, compared using t test with 95 percent confidence intervals, p 0.05. Result: Use chemical outside permitted list as Wolfatox still a significant proportion in the two communes of Vinh Loc and Vinh Quang (9.6 percent and 8.3 percent). The indicators on knowledge and practice safe use chemical significant difference before and after intervention and between rontrol and intervention group. Conclusion: to improve knowledge and practice safe use chemical pesticides by training, propaganda, handouts to the community with supervision is appropriate and effective.