Three non-alkaloidal metabolites, stemanthrene C, p-anisic and benzoic acids, were isolated from the roots of Stemontl peirrei plants, collected in Savannakhet province (Laos). Their structures were elucidated by spectroscopic analyses. Stemanthrene C exhibited medium cytotoxic activity against KB cell line with IC50 value of 82.03 ug/ml.