Besides the major syndromes such as neonatal respiratory distress, neonatal infections, the newborn Jaundice is a common syndrome in pediatric practice daily. Patients should be diagnosed and treated properly to avoid children with life-threatening or life with severe neurological sequelae. To explore the clinical characteristics subclinical premature newborn jaundice hyperbilirubinemia freedom. The author conducted a study on 310 preterm newborn jaundice treated at pediatric hospitals in the state central cross-sectional descriptive methods. The results showed that the majority of jaundice appear 49-72 hours after birth, jaundice is detected when the golden child 3, the 4, still young jaundice is detected late when symptoms had damage brain injury, with a positive correlation between the degree of clinical jaundice and hyperbilirubinemia freedom. Jaundice occurs mainly in children whose mothers take a blood group, blood type B child bearing, children as young as lower weight, lower blood bilirubin levels, children show signs of brain damage when bilirubin average 261.75 + or - 100.8, indirect bilirubin average 247.72 + or - 95.79. 37.1 percent have no countervailing factors mother ABO blood group, 99.6 percent of children with jaundice after birth with respiratory distress, jaundice 40.4 percent of children had not found the cause, 22.6 percent had blood group factor antagonists mother ABO, down 17.1 percent mom amniotic leak in 6 hours, only 6.5 percent have .used drugs birth mother (oxytocin). And 13.3 percent of children were jaundiced assessment of clinical jaundice with a bilirubin is not proportionate at the same time. In infants less than 35 weeks may reduce the frequency of blood proteins albumin and more children aged 35 weeks to less than 37 weeks.