Formaldehyde (HCHO) is a widely used compound in various industries, including construction, automotive production, and interior decoration fields. However, HCHO is much concerned as a harmful substance that can negatively impact human health, even at low concentrations, in extended periods of exposure. Therefore, the detection of HCHO at low concentrations is crucial. In this study, copper-modified cryptomelane (Cu-OMS-2) was synthesized by reflux method. Cu-OMS-2 electrode exhibited the ability ofHCHO detection at a concentration of 1 mM by electrochemical analysis method. A shift in the reduction peak (from -0.6 to 0.0 V) was observed with increase of HCHO concentrations (from 1 to 5 mM). A linear relationship between these two variables was established, described by the equation y = -0.7023.x + 0.1321, with a high correlation coefficient (R2 = 0.99). These results demonstrate the potential of Cu-OMS-2 material for the electrochemical detection of HCHO at low concentration.