The cross sectional study was conducted on 60 in and out-patients in Hochiminh traditional mediphamarceutical institute from Oct 2011 to March 2012. The objective was aimed at: 1/ To evaluate the efficacy of Khuphongtruthap medication therapy on patients with neck-shoulder arm syndrome due to neck vertebrea degeneration
2/ To investigate the side effects of khuphongtruthap tablets. The data was collected through protocol in patient's chart and medical records including lab tests. The results showed pain reduced dramatically after 20 days of treatment. The severe pain falls from 20 percent to 8,4 percent. The moderate and mild pain also markedly decreased. For the neck physical exercise, there was not any limitation in neck flexion, extension, rotation, lateral flexion. There was significantly difference between before and after treatment with p 0,05.