Background: Cirrhosis is a leading cause of low blood albumin and clotting disorders, and there are many other causes of low blood protein. Objectives: To review variable plasma protein concentration and a majority stop bleeding after treatment with FFP in the patients with cirrhosis and low blood albumin due to some other causes. Subject and Method: 53 patients with liver cirrhosis and 36 patients with low blood albumin by kidney disease and other chronic diseases were treated with the combination regimen - tracking FFP 2 weeks of treatment. Results: The serum protein and albumin in patients with cirrhosis group increased from 55.82 + or - 6.83 and 22.29 + or - 3.34 to 65.26 + or - 9.28 and 29.22 + or - 4.77 g/I (p 0.05) respectively
in the group without hepatic dysfunction increased from 51.35 + or - 6.92 and 24.38 + or - 4.23 g/I to 60.12 + or - 5.22 and 31.44 + or - 4,53 g/I respectively. Prothrombin ratio, APTT and platelets seemed to change, but not statistically significant (as for the cirrhosis group), with statistically significant but still within the normal range (as for the group without hepatic dysfunction). Conclusion: The treatment of cirrhosis and low blood albumin caused by FFP improves protein concentration and the coagulation index.