The decay of SM-like Higgs boson in the G221 model which is one of all models beyond the SM (BSM) has been investigated. This decay channel has not been observed experimentally. In the framework, we indicate that new particles predicted by this model may significantly affect the previously mentioned decay channel of the SM-like Higgs boson. We will study the effects of the new heavy-charged boson, the charged Higgs boson was not included previously. We are namely, contributing from the diagram both Higgs boson and charged boson. The calculated results are expressed in terms of Passarino-Veltman functions, the numerical evaluation of which can be obtained using LoopTools. Our numerical investigation presents some details and properties of this decay. These may prove useful for comparison with future experimental results that could be detected.