Khảo sát sơ bộ thành phần hóa thực vật và một số hoạt tính sinh học cao chiết ethanol của cây Mua thấp (Melastoma dodecandrum Lour. Melastomaceae)=Study on phytochemistry screening and bioativities testing on Ethanol extract of Melastoma dodecandrum Lour. Melastomaceae

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Tác giả: Trung Hải Lê, Hoàng Khánh Linh Nguyễn, Anh Thư Trần

Ngôn ngữ: vie

Ký hiệu phân loại:

Thông tin xuất bản: Tạp chí Khoa học và Công nghệ - Đại học Nguyễn Tất Thành, 2024

Mô tả vật lý: tr.51

Bộ sưu tập: Metadata

ID: 484251

Thêm vào giỏ

Nghiên cứu này được thực hiện nhằm khảo sát sơ bộ thành phần hóa học và một số hoạt tính sinh học của dược liệu Mua thấp từ cao chiết ethanol 80 %. Sơ bộ hóa thực vật dược liệu bằng phương pháp Ciuley cải tiến bởi Trường Đại học Y Dược Thành phố Hồ Chí Minh. Chiết xuất cao toàn phần Mua thấp bằng phương pháp chiết ngấm kiệt với cồn 80 % ở nhiệt độ phòng. Thử hoạt tính chống bệnh tiểu đường trên enzyme α-glucosidase, kháng viêm và chống oxy hóa trên mô hình DPPH. Kết quả nghiên cứu cung cấp một số thông tin chưa được nghiên cứu về dược liệu Mua thấp, giúp xác định tiềm năng của loài dược liệu này trong phòng ngừa và điều trị bệnh. Nghiên cứu đã sử dụng các phương pháp định tính để nghiên cứu các hợp chất tồn tại trong cây Mua thấp và chứng minh khả năng chống bệnh tiểu đường, kháng viêm và chống oxy hóa.This study aimed to investigate the chemical composition and biological activities of Melastoma dodecandrum Lour. (Melastomaceae) – a medicinal herb, through its 80% ethanol extract. A preliminary phytochemical analysis was performed using an adapted version of the Ciuley method developed by the University of Medicine and Pharmacy, Ho Chi Minh City. The total extract was obtained via 80% ethanol extraction at room temperature. The anti-diabetic potential of the extract was evaluated through inhibition of the α-glucosidase enzyme, while anti-inflammatory and antioxidant activities were assessed using the DPPH radical scavenging model. The findings contribute novel information about Melastoma dodecandrum, highlighting its potential in disease prevention and treatment. The phytochemical screening confirmed the presence of chemical compounds existing in this plant, supporting its anti-diabetic, anti-inflammatory, and antioxidant properties.

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