Nghiên cứu một số chỉ số xét nghiệm của bệnh nhân đa u tuỷ xương chuỗi nhẹ tại bệnh viện bạch mai

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Tác giả: Thị Minh Tâm Hà, Trà My Hà, Nguyệt Mai Hứa, Văn Hưng Mai, Thị Phương Oanh Ngô, Mỹ Linh Tạ

Ngôn ngữ: vie; Vie

Ký hiệu phân loại: 362 Social welfare problems and services

Thông tin xuất bản: Khoa học và công nghệ (đại học thái nguyên), 2017

Mô tả vật lý: 144-153, 146-150, 181-185

Bộ sưu tập: Metadata

ID: 484904

Thêm vào giỏ

Đa u tuỷ xương chuỗi nhẹ (LCMM) chiếm khoảng 15-20% bệnh nhân đa u tuỷ, có tiên lượng xấu, đáp ứng điều trị kém hơn so với các nhóm khác, khó phát hiện sớm ở các bệnh viện không phải tuyến chuyên khoa, bệnh nhân thường được chẩn đoán bệnh muộn có nhiều biến chứng (thiếu máu, suy thận, loãng xương). Để chẩn đoán sớm và kịp thời, các nghiên cứu về đặc điểm các xét nghiệm cơ bản thường gặp của bệnh nhân mắc LCMM là vô cùng cần thiết. Mục tiêu: nghiên cứu một số chỉ số xét nghiệm của bệnh nhân LCMM đến khám và điều trị tại Bệnh viện Bạch Mai. Đối tượng, phương pháp nghiên cứu: Nghiên cứu mô tả cắt ngang trên 50 bệnh nhân mới chẩn đoán LCMM từ 01/2018 đến 07/2022, điều trị tại Bệnh viện Bạch Mai. Kết quả: Bệnh nhân LCMM có biểu hiện tăng protein máu, giảm albumin máu, và chỉ số A/G đảo ngược tỷ lệ thấp, lần lượt là 2%, 8% và 16%. Tỷ lệ bệnh nhân tăng beta-2-microglobulin chiếm 82%. Tỷ lệ bệnh nhân có chỉ số LDH bình thường chiếm 96%. Tỷ lệ bệnh nhân có chỉ số Calci toàn phần bình thường chiếm 82%. Kết luận: Các xét nghiệm của bệnh nhân LCMM có biểu hiện tăng protein máu và beta-2-microglobulin, giảm albumin máu, chỉ số A/G đảo ngược tỷ lệ thấp, LDH và Calci toàn phần bình thường., Tóm tắt tiếng anh, Light chain multiple myeloma (LCMM) accounts for about 15-20% of patients with multiple myeloma, has a poor prognosis, has a poorer response to treatment than other groups, and is difficult to detect early in hospitals, patients are often diagnosed late with many complications (anemia, kidney failure, osteoporosis). For early and timely diagnosis, studies on the characteristics of common basic tests of patients with LCMM are essential. Objectives: Research of some laboratory indicators of LCMM patients who come for examination and treatment at Bach Mai Hospital. Subjects, research methods: A cross-sectional descriptive study on 50 patients newly diagnosed with LCMM from 01/2018 to 07/2022, treated at Bach Mai Hospital. Results: Patients with LCMM had low rates of hyperproteinemia, hypoalbuminemia, and A/G inversion, 2%, 8%, and 16%, respectively. The proportion of patients with increased beta-2-microglobulin accounted for 82%. The proportion of patients with normal LDH index accounted for 96%. The proportion of patients with normal total calcium index accounted for 82%. Conclusion: The laboratory indicators of LCMM patients showed hyperproteinemia and beta-2-microglobulin, hypoalbuminemia, low A/G ratio reversed, LDH and total calcium were normal. Nghiên cứu một số chỉ số sinh học của trẻ em Trường mần non 1/5, thành phố Thái Nguyên, tỉnh Thái Nguyên. Kết quả cho thấy các chỉ số về chiều cao, cân nặng, vòng ngực đều tăng dần theo độ tuổi. Trong từng độ tuổi, các chỉ số này của trẻ em nam lớn hơn trẻ em nữ. Chỉ số Pignet của trẻ ở các độ tuổi đều đạt mức thể lực rất khỏe, khỏe và trung bình. The article studies some biological indicators of children in the Nursery School 1/5, Thai Nguyen city, Thai Nguyen province. The results showed that the indicators of height, weight and chest height gradually increased with age. In each age, these indicators of male children are larger than female children. The Pignet index of children of all ages reaches a healthy, healthy and average fitness level. This study examined 2177 high school students in Northeastern Vietnam to evaluate anthropometric indexes, including weight-for-age, height-for-age, head circumference-for-age, neck circumference-for-age, mid-upper arm circumference-tar-age, chest circumference-tar-age, abdomen circumference-tar-age and hip circumference-for-age. The results showed that: (1) The development of these anthropometric parameters in Northeastern Vietnam corresponds to general body growth of Vietnamese people, (2) These anthropometric parameters correlate with each other in regarding growth process in ages 16 to 18, (3) Most of the children have a BMI which is average (92.7 percent of the 16 year olds, 90.2 percent of the 17 year oids and 957 percent of the 18 year oIds). However, some students were stunted (2.0 percent of the 16 year olds, 2.8 percent of the 17 year olds and 1.5 percent of the 18 year olds.The percent of those who were overweigh rate was 3.5 percent, 5.2 percent and 1.6 percent and percent who were obese was 0.8 percent, 0.9 percent and 0.4 percent, respectively, lor those 16 to 18 years old.

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