This article, for the very first time, has published the result of a study about amphibians and reptiles in Tien Giang province. A total list includes 62 species of amphibians and reptiles belonging to 44 genus, 21 families and 5 orders distributing in this study area. Among which, there are 17 rare and endangered species which are listed in Vietnam's Red Book, IUCN Red List, Decree 32 of the Government, and Convention CITES. There are 23 species which are currently being exploited for usage and business purposes.