KHẢO SÁT HOẠT TÍNH CHỐNG OXY HOÁ CỦA CAO FLAVONOID TỪ LÁ BẦN CHUA (SONNERATIA CASEOLARIS)=ANTIOXIDANT POTENTIAL OF FLAVONOIDS EXTRACTED FROM MANGROVE APPLE LEAVES (SONNERATIA CASEOLARIS)

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Tác giả: Văn Hậu Đoàn, Như Thạch Hồ, Thị Thanh Lệ Trịnh

Ngôn ngữ: vie

Ký hiệu phân loại:

Thông tin xuất bản: Tạp chí Khoa học - Đại học Thủ Dầu Một, 2024

Mô tả vật lý: tr.110-117

Bộ sưu tập: Metadata

ID: 484979

Thêm vào giỏ

Cây bần chua hay bần sẻ được trồng nhiều ở khu vực ven biển và ven sông, đặc biệt cây rất thích hợp với vùng nước lợ ở Việt Nam có tên khoa học là Sonneratia caseolaris (L.) Engl., thuộc họ Sonneratiaceae. Nghiên cứu này nhằm đánh giá khả năng chống oxy hoá của cao flavonoid chiết xuất từ lá bần chua. Bột lá bần chua được chiết xuất bằng phương pháp siêu âm trong ethanol 70%, dịch chiết sau đó được đông khô trong điều kiện áp suất giảm dần. Nghiên cứu đã tiến hành định lượng flavonoid tổng và khảo sát khả năng chống oxy hóa bằng phương pháp trung hoà gốc tự do DPPH và ABTS. Kết quả định lượng cho thấy cao có hàm lượng flavonoid tổng là 140,73mg QE/g cao khô. Khả năng trung hoà gốc tự do DPPH và ABTS cao của cao flavonoid lá bần chua được thể hiện qua giá trị ức chế 50% (IC50) lần lượt là 10,42 ± 0,35µg/mL và 9,63 ± 0,16µg/mL. Kết quả nghiên cứu cho thấy cao flavonoid lá bần chua có khả năng chống oxy hoá, khả năng này có thể góp phần tạo nên những tác dụng hữu ích trong hỗ trợ điều trị các bệnh có liên quan đến sự mất cân bằng oxy hoá trong cơ thể.Mangrove apple, also called crabapple mangrove, is popular growth in the coastal or riverside areas, especially in saltwater area in Viet Nam. The scientific name is Sonneratia caseolaris (L.) Engl. which belongs to the family of Sonneratiaceae. This study aimed to investigate the antioxidant potential of flavonoids extracted from S. caseolaris leaves. S. caseolaris leaves powder was extracted by ultrasonic method in ethanol 70%, the extract was freeze-dried under reducing pressure then. Total flavonoids were measured and in vitro antioxidant potential of the extract was evaluated by DPPH and ABTS assays. The result showed that total flavonoid contents in the extract was 140,73mg QE/g dried extract. Free radical scavenging activity of the extract to DPPH and ABTS were determined with IC50 = 10.42 ± 0.35µg/mL and 9.63 ± 0.16µg/mL, respectively. These results revealed the antioxidant potential of flavonoids extracted from S. caseolaris leaves. This ability may contribute to helpful effects in the treatment of diseases related to oxidative imbalance conditions in humans.

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