Therapeutic inertia in lipid management among Polish adults with type 1 diabetes - results from the cross-sectional PARADISE T1DM study.

 0 Người đánh giá. Xếp hạng trung bình 0

Tác giả: Justyna Flotyńska, Mikołaj Kamiński, Dominika Kasprzak, Daria Klause, Maria Kozłowska, Anna Kulczycka, Michał Kulecki, Paweł Lachowski, Dariusz Naskręt, Aleksandra Uruska, Dorota Zozulińska-Ziółkiewicz

Ngôn ngữ: eng

Ký hiệu phân loại:

Thông tin xuất bản: Netherlands : Nutrition, metabolism, and cardiovascular diseases : NMCD , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 48659

BACKGROUND AND AIMS: Adults with Type 1 diabetes (T1DM) have increased cardiovascular risk. Most of the Polish general population fails to meet lipid goals. Recent data on the effectiveness of dyslipidemia treatment in T1DM population is lacking. We aimed to investigate which part of adults with T1DM met the dyslipidemia treatment goals according to the European Society of Cardiology (ESC) and European Atherosclerosis Society (EAS) 2016 and 2019 guidelines. METHODS AND RESULTS: We recruited adult people with T1DM, for whom a cross-sectional assessment of disease progression was performed. Anthropometric measurements and a basic panel of laboratory tests were conducted for each person. We assessed cardiovascular risk and lipid goals according to the ESC/EAS dyslipidemia guidelines from 2016 to 2019. Among the n = 233 participants, only 34.3 % met the lipid goal according to the 2016 guidelines, while for the 2019 guidelines, merely 13.3 %. Only 12.8 % of individuals with very high cardiovascular risk met the LDL cholesterol goals according to ESC/AES 2016, and 4.9 % when ESC/EAS 2019 guidelines were considered. The median difference between the LDL cholesterol value and the target value was 18.0 (-16.0 to 49.0) mg/dl [20.4 % (-19.8 %-41.2 %)], when considering the 2016 ESC/EAS guidelines, whereas for the 2019 guidelines, it was 36.0 (11.0-60.0) mg/dl [36.3 % (13.9 %-48.0 %)]. CONCLUSION: Therapeutic inertia results in the failure to meet the lipid goals according to the ESC/EAS guidelines for 2016 and 2019 in most Polish adults with T1DM. Many adults with T1DM may require intensification of lipid-lowering interventions.
Tạo bộ sưu tập với mã QR

THƯ VIỆN - TRƯỜNG ĐẠI HỌC CÔNG NGHỆ TP.HCM

ĐT: (028) 36225755 | Email: tt.thuvien@hutech.edu.vn

Copyright @2024 THƯ VIỆN HUTECH