NHẬN XÉT LIÊN QUAN GIỮA CÁC THÔNG SỐ BẢN ĐỒ T1, T2 VỚI BỀ DÀY THÀNH TIM VÀ NGẤM THUỐC CƠ TIM THÌ MUỘN TRÊN CỘNG HƯỞNG TỪ 3.0 TESLA Ở BỆNH NHÂN BỆNH CƠ TIM PHÌ ĐẠI=Relation between T1 and T2 mapping with wall thickness and late gadolinium enhancement of myocardial segments in patients with hypertrophic cardiomyopathy on 3 Tesla magnetic resonance imaging

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Tác giả: Văn Thường Đỗ, Thị Ngân Dương, Diệu Linh Hoàng, Thị Vân Hoa Hoàng, Thị Thuỳ Liên Lê, Công Tiến Nguyễn, Khôi Việt Nguyễn, Ngọc Tráng Nguyễn, Thị Huyền Nguyễn, Minh Thông Phạm, Bảo Ngọc Phùng, Thị Lý Trần, Thị Quỳnh Trần, Thị Trang Trần, Đăng Lưu Vũ

Ngôn ngữ: vie

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Thông tin xuất bản: Tạp chí Điện quang và Y học hạt nhân Việt Nam, 2024

Mô tả vật lý: tr.21-29

Bộ sưu tập: Metadata

ID: 487000

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Mục tiêu: Khảo sát các thông số bản đồ T1, T2 trên cộng hưởng từ (CHT) 3.0 Tesla theo phân đoạn cơ tim ở bệnh nhân bệnh cơ tim phì đại (BCTPĐ).Đối tượng và phương pháp: Nghiên cứu tiến cứu 22 bệnh nhân BCTPĐ với các chuỗi xung cine, bản đồ T1 native và sau tiêm, bản đồ T2 và chuỗi xung ngấm thuốc thì muộn (LGE) tại bệnh viện Bạch Mai từ tháng 8/2023 đến tháng 8/2024.Kết quả: 68 % nam, tuổi trung bình là 50,55 ± 18,79 tuổi. Tổng số 352 phân đoạn cơ tim, có 50 phân đoạn (14,2%) có hình ảnh ngấm thuốc thì muộn (LGE). Giá trị T1 native tăng ở các phân đoạn không phì đại, các phân đoạn phì đại nhẹ, vừa và nặng với giá trị trung bình lần lượt là 1215,17 ± 33,01 ms, 1281,69 ± 15,48ms, 1332,07 ± 11,24 ms và 1378,71 ± 16,74 ms. Giá trị T1 native của các phân đoạn cơ tim có ngấm thuốc muộn cao hơn đáng kể so với các phân đoạn không có với p <
0,001. Giá trị T2 chỉ tăng ở các phân đoạn phì đại trung bình và nặng với giá trị trung bình lần lượt là 49,76 ± 5,3 ms và 48,13 ± 9,8 ms.Kết luận: Giá trị T1 native và T2 tăng trong BCTPĐ, có thể cung cấp công cụ hữu ích trong chẩn đoán sớm tái cấu trúc cơ tim.Objective: To investigate T1 and T2 mapping values of local myocardial segments on 3 Tesla Magnetic Resonance Imaging, in patients with hypertrophic cardiomyopathy (HCM).Methods: A prospective- cross-sectional descriptive study recruited 22 patients diagnosed with HCM who underwent 3T Magnetic Resonance at Bach Mai Hospital from 08/2023 to 08/2024.Results: 68% men, mean age was 50.55 ± 18.79 years. Native T1 values increased in non-hypertrophic, mild, moderate, and severe hypertrophic segments, with the mean values are 1215.17 ± 33.01 ms, 1281.69 ± 15.48ms, 1332.07 ± 11.24 ms and 1378.71 ± 16.74 ms respectively. The mean native T1 values of myocardial segments with LGE were significantly higher than those without LGE, with p <
0.001. The average T2 value increased in the moderate and severe hypertrophysegments with mean values are 49.76 ± 5.30 ms and 48.13 ± 9.80 ms, respectively. Of a total of 352 myocardial segments, 50 segments (14.2%) had late gadolinium enhancement (LGE).Conclusions: Native T1 and T2 mapping values can provide additional value for HCM diagnosis at an early stage.

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