Giá trị dự báo đái tháo đường thai kỳ của siêu âm đo bề dày mỡ bụng ở thai phụ mang thai quý I=The predictive value of gestational diabetes mellitus of ultrasound measurement of abdominal fat thickness in pregnant women in the first trimester of pregnancy

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Tác giả: Tùng Lâm Bùi, Văn Hiếu Bùi, Đình Lý Nguyễn, Nhóm Daht 28, Khắc Quang Trần

Ngôn ngữ: vie

Ký hiệu phân loại:

Thông tin xuất bản: Tạp chí Khoa học Sức khỏe, 2024

Mô tả vật lý: tr.49

Bộ sưu tập: Metadata

ID: 487190

Thêm vào giỏ

Mục tiêu: Xác định giá trị tiên lượng siêu âm độ dày mỡ bụng của thai phụ mang thai từ 11 tuần 00 ngày đến 13 tuần 06 ngày với nguy cơ với đái tháo đường thai kỳ (ĐTĐTK). Phương pháp nghiên cứu: Nghiên cứu trên 246 thai phụ quản lý thai tại Bệnh viện Quốc tế Sản Nhi Hải Phòng và Khoa sản Bệnh viện Đại học Y Hải Phòng, được đo bề dày mỡ bụng từ 11 tuần đến 13 tuần 06 ngày, sau đó được làm xét nghiệm sàng lọc đái tháo đường thai kỳ lúc 24-28 tuần. Kết quả nghiên cứu: Đối tượng nghiên cứu chủ yếu nằm trong độ tuổi sinh sản (25-34 tuổi) chiếm 67,48%. Chỉ số khối (BMI) khi mang thai chủ yếu là bình thường (62,6%), nhóm thừa cân béo phì chiếm 16,26%. Thai phụ có độ dày mỡ bụng ≥ 20 mm có nguy cơ mắc ĐTĐTK cao hơn 10,67 lần so với nhóm <
20 mm (OR = 10,67
95%CI: 4,38 – 26
p <
0,01). Tại điểm cut-off độ dày mỡ bụng là 20mm có giá trị dự báo ĐTĐTK ở quý 1 với độ nhaỵ, độ đặc hiệu lần lượt là 63,64% và 85,92% cùng giá trị tiên đoán 82,93%, AUC = 0,75 có ý nghĩa thống kê với p<
0,001. Kết luận: Độ dày mỡ bụng trên siêu âm là một chỉ số dễ thực hiện có thể là một chỉ số tiềm năng cùng với các yếu tố khác để tiên lượng ĐTĐTK sớm.Objective: To determine the prognostic value of abdominal fat thickness measured by ultrasound in predicting the risk of gestational diabetes mellitus (GDM). Methods: A study was conducted on 246 pregnant women receiving antenatal care at Hai Phong International Obstetrics and Pediatrics Hospital and the Department of Obstetrics, Hai Phong University of Medicine and Pharmacy Hospital. Abdominal fat thickness was measured between 11 weeks and 13 weeks 6 days of gestation. The participants were subsequently monitored and underwent screening tests for GDM. Results: The majority of the study participants were of reproductive age (25-34 years), accounting for 67.48%. Most pregnant women had a normal body mass index (BMI) (62.6%), while 16.26% were overweight or obese. Pregnant women with an abdominal fat thickness of ≥ 20 mm had a 10.67 times higher risk of developing GDM compared to those with <
20 mm (OR = 10.67
95% CI: 4.38 – 26
p <
0.01). At the cut-off point of 20 mm, first-trimester abdominal fat thickness had a predictive value for GDM with a sensitivity of 63.64%, specificity of 85.92%, and a predictive value of 82.93%, with an AUC of 0.75 (p <
0.001). Conclusion: Ultrasound-measured abdominal fat thickness is an easily obtainable parameter that may serve as a potential indicator, along with other factors, for the early prediction of GDM.

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