Associations between pre- and post-diagnosis dietary inflammatory patterns and ovarian cancer survival: results from the Ovarian Cancer Follow-Up Study.

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Tác giả: Qi Bao, Rui-Han Bao, Yu-Han Chen, Song Gao, Ting-Ting Gong, Dong-Hui Huang, Xiao-Ying Li, Yi-Zi Li, Chuan Liu, Fang-Hua Liu, Jia-Ming Liu, Jia-Xin Liu, Meng Luan, Jia-Yi Wang, Xiao-Ying Wang, Yi-Fan Wei, Lang Wu, Qi-Jun Wu, Qian Xiao, He-Li Xu, De-Yu Zhang

Ngôn ngữ: eng

Ký hiệu phân loại: 133.594 Types or schools of astrology originating in or associated with a

Thông tin xuất bản: United States : Journal of the Academy of Nutrition and Dietetics , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 488213

BACKGROUND: Dietary factors impact systemic inflammation, which not only correlates with poorer outcomes in patients with ovarian cancer (OC) but also promotes cancer development through increased cell division, genetic alterations, and malignant transformation of epithelial cells at inflammatory sites. However, evidence between dietary inflammatory patterns and OC survival remains sparse. OBJECTIVE: The aim of this study was to examine associations between pre- and post-diagnosis dietary inflammatory patterns, including their changes, and overall survival (OS). DESIGN: This study analyzed data from the hospital-based prospective, longitudinal cohort study: the Ovarian Cancer Follow-Up Study. Dietary intake information was collected at baseline (pre-diagnosis) and 12 months following diagnosis (post-diagnosis) using a 111-item food frequency questionnaire. Three inflammatory dietary scores were analyzed: dietary inflammatory index (DII), inflammatory score of the diet (ISD), and empirical dietary inflammatory pattern (EDIP). The dietary inflammatory scores were calculated for each person and categorized in tertiles. PARTICIPANTS/SETTING: Participants included 560 patients 18-79 years of age, who were newly diagnosed with OC, recruited at the Shengjing Hospital of China Medical University between 2015 and 2022. MAIN OUTCOME MEASURES: OS time was defined as the interval between the histological diagnosis of OC and the date of death from any cause or the date of last follow-up (February 16, 2023) for patients who were still alive. STATISTICAL ANALYSES PERFORMED: Differences in general and clinical characteristics according to the tertile of inflammatory dietary pattern scores were assessed using χ RESULTS: High pre-diagnosis DII, ISD, and EDIP scores were associated with worse OS (HRs CONCLUSIONS: Pre- and post-diagnosis adherence to inflammatory dietary patterns was associated with poor OC survival.
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