Nghiên cứu một số đặc điểm của vi khuẩn lao ở bệnh nhân lao phổi mới và lao phổi tái trị được chỉ định điều trị bằng thuốc chống lao hàng một

0 Người đánh giá. Xếp hạng trung bình 0

Tác giả: Văn Khoa Đặng, Mạnh Chiến Giang, Thị Luyến Lê, Phượng Hoàng Nguyễn, Văn Hưng Nguyễn, Hữu Thường Phạm, Thị Thu Huyền Phạm, Thị Hiền Trịnh

Ngôn ngữ: vie

Ký hiệu phân loại: 612 Human physiology

Thông tin xuất bản: Khoa học và công nghệ việt nam, 2018

Mô tả vật lý: 1-5

Bộ sưu tập: Metadata

ID: 488489

Thêm vào giỏ Liên kết toàn văn

Tóm tắt
Chủ đề

Mục tiêu của nghiên cứu là đánh giá đặc điểm vi khuẩn lao dựa trên kết quả xét nghiệm vi sinh ở bệnh nhân (BN) lao phổi mới và tái trị được chỉ định điều trị bằng thuốc chống lao hàng 1. Phương pháp thực hiện: Nghiên cứu mô tả, so sánh kết quả xét nghiệm vi khuẩn lao của bệnh nhân lao phổi mới và tái trị. Nghiên cứu được tiến hành trên 64 bệnh nhân lao phổi mới, 39 BN lao phổi tái trị điều trị tại Bệnh viện Phổi Hà Nội và Bệnh viện 74 Trung ương. Kết quả cho thấy, không có sự khác biệt về kết quả xét nghiệm vi khuẩn lao bằng nhuộm soi trực tiếp và nuôi cấy nhóm lao phổi mới và lao phổi tái trị. Tỷ lệ kháng thuốc chống lao hàng 1 của vi khuẩn lao phân lập từ bệnh nhân lao tái trị (53,85%) cao hơn lao mới (21,88%). Mặc dù được loại trừ nhanh đa kháng thuốc bằng GenXpert nhưng có 1 bệnh nhân lao mới và 5 bệnh nhân lao tái tri được xác định đa kháng thuốc bằng kháng sinh đồ. Qua nghiên cứu có thể kết luận: Vi khuẩn lao phân lập từ đờm của nhóm bệnh nhân lao phổi tái trị có tỷ lệ kháng thuốc chống lao hàng 1 cao hơn nhóm bệnh nhân lao mới.The objective of the study was to assess the characteristics of tuberculosis bacteria based on the results of microbiological testing in patients with new and re-treated pulmonary tuberculosis who were prescribed anti-tuberculosis drug treatment 1. Method of implementation: Descriptive study, comparing the results of TB bacteriological testing of patients with new and re-treated tuberculosis. The study was conducted on 64 new pulmonary tuberculosis patients, 39 tuberculosis patients re-treated at Hanoi Lung Hospital and Central Hospital 74. The results showed that there was no difference in the test results of TB bacteria by direct staining and culture of new pulmonary tuberculosis group and re-treated pulmonary tuberculosis. The rate of resistance to TB tuberculosis row 1 of tuberculosis bacteria isolated from re-treated tuberculosis patients (53.85%) was higher than that of new tuberculosis (21.88%). Despite the rapid elimination of multi-drug resistance by GenXpert, 1 new TB patient and 5 re-TB patients were identified as multi-drug resistance using antibiotics. Through the study, it can be concluded that: Tuberculosis bacteria isolated from sputum of patients with re-treated pulmonary tuberculosis have a higher rate of resistance to tuberculosis row 1 than the new group of TB patients.

Tạo bộ sưu tập với mã QR