Xác định perfluorooctanoic acid (pfoa) và perfluorooctane sulfonic acid (pfos) trong bao bì thực phẩm bằng giấy

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Tác giả: Thu Hiền Đặng, Thị Thu Hằng Đỗ, Duy Khánh Đoàn, Quốc Anh Hoàng, Thị Lan Phương Kiều, Hữu Tuyến Lê, Thị Ánh Hường Nguyễn, Thị Quỳnh Hoa Nguyễn, Thị Liễu Trần

Ngôn ngữ: vie

Ký hiệu phân loại: 614 Forensic medicine; incidence of injuries, wounds, disease; public preventive medicine

Thông tin xuất bản: Tạp chí kiểm nghiệm và an toàn thực phẩm, 2022

Mô tả vật lý: 589-597

Bộ sưu tập: Metadata

ID: 489227

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In this study, a method for simultaneous determination of perfluorooctanoic acid (PFOA) and perfluorooctane sulfonic acid (PFOS) by liquid chromatography-tandem mass spectrometry (LC-MS/MS) in paper-based food packaging was validated. The paper samples were extracted with ethanol/water (1 (:) 1, v/v) mixture at 70°C for 2 h by using an incubator shaker. The extracts were passed through 0.2 μm filters before LC-MS/MS analysis. The method detection limit and method quantification limit of both PFOA and PFOS were 0.1 and 0.3 ng/g, respectively. Correlation coefficients và gt
0.99 were obtained over concentration ranges from 0.3 to 10 ng/mL. The method recovery ranged from 100 - 106% with good repeatability (RSD và lt
5%). The method was applied to analyze 23 paper samples, however, PFOA and PFOS were not detected in any of these samples.Trong nghiên cứu này, phương pháp phân tích đồng thời perfluorooctanoic acid (PFOA) và perfluorooctane sulfonic acid (PFOS) bằng thiết bị sắc ký lỏng khối phổ hai lần (LC-MS/MS) trong bao bì thực phẩm giấy đã được thẩm định. Các mẫu bao bì giấy được chiết với hỗn hợp ethanol (:) nước (1 (:) 1, v/v) ở nhiệt độ 70°C trong 2 h. Dịch chiết được lọc qua màng lọc 0,2 μm trước khi phân tích trên thiết bị LC-MS/MS. Giới hạn phát hiện và giới hạn định lượng của phương pháp lần lượt là 0,1 và 0,3 ng/g đối với 2 chất phân tích. Hệ số tương quan tuyến tính đạt R và gt
0,99 trong khoảng nồng độ 0,3 đến 10 ng/mL. Độ thu hồi của phương pháp dao động trong khoảng từ 100 - 106% với độ lặp lại RSD và lt
5%. Phương pháp đã được ứng dụng để phân tích 23 mẫu bao bì thực phẩm bằng giấy nhưng không mẫu nào phát hiện thấy PFOS và PFOA.

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